Publications at UVA

1. Fields, W. H.; Khan, A. K.; Sabat, M.; Chruma, J. J.* "One Pot Tandem Decarboxylative Allylation–Heck Cyclization of Allyl Diphenylglycinate Imines: Rapid Access to Polyfunctionalized 1-Aminoindanes", Org. Lett. 2008, 10, 5131-5134. doi: 10.1021/ol801986m .

2. Yeagley A. A.; Archibald, M. M.; Chruma, J. J.* "Palladium-Catalyzed Decarboxylative Michael Addition-Allylation of Allyl Diphenylglycinate Imines and Activated Olefins", manuscript in preparation.

3. Yeagley, A. A.; Chruma, J. J.* "C–C Bond-Forming Reactions via Pd-Mediated Decarboxylative a-Imino Anion Generation", Org. Lett. 2007, 9, 2879–2882. doi: 10.1021/ol071080f.

Publications prior to UVA

4. Chruma, J. J.; Liu, L.; Zhou, W.; Breslow, R.* "Hydrophobic and Electronic Factors in the Design of Dialkylglycine Decarboxylase Mimcs", Bioorg. Med. Chem. 2005, 13, 5873–5883. doi: 10.1016/j.bmc/2005.05.019.

5. Zhou, W.; Yerkes, N.; Chruma, J. J.; Liu, L.; Breslow, R.* "Chiral Polyamines from Reduction of Polypeptides: Asymmetric Pyridoxamine-Mediated Transaminations", Bioorg. Med. Chem. Lett. 2005, 15, 1351–1355. doi: 10.1016/j.bmcl.2005.01.021.

6. Liu, L.; Zhou, W.; Chruma, J.; Breslow, R.* "Tranamination Reactions with Multiple Turnovers Catalyzed by Hydrophobic Pyridoxamine Cofactors in the Presence of Polyethylene-imine Polymers. J. Am. Chem. Soc. 2004, 126, 8136–8137. doi: 10.1021/ja048671a.

7. Si, Z.; Madani, N.;Cox, J. M.; Chruma, J. J.; Klein, J. C.; Schˆn, A.; Phan, N.; Wang, L.; Biorn, A. C.; Cocklin, S.; Chaiken, I.; Freire, E.; Smith, A.B., III; Sodroski, J. G.* "Small-Molecule Inhibitors of HIV-1 Entry Block Receptor-Induced Conformational Changes in the Viral Envelope Glycoproteins", Proc. Nat. Acad. Sci. USA 2004, 101, 5036–5041. doi: 10.1073/pnas.0307953101.

8. Madani, N.; Perdigoto, A. L.; Srinivasan, K.; Cox, J. M.; Chruma, J. J.; LaLonde, J.; Head, M.; Smith, A. B., III; Sodroski, J. G.* "Localized Changes in the gp120 Envelope Glycoprotein Confer Resistance to Human Immunodeficiency Virus Entry Inhibitors BMS-806 and #155", J. Virol. 2004, 78, 3742–3752. doi: 10.1128/JVI.78.7.3742-3752.2004.

9. Smith, A. B., III;* Chruma, J. J.; Han, Q.; Barbosa, J. "Complestatin Synthetic Studies: The Effect of the Amino Acid Configuration on Peptide Backbone Conformation in the Common Western BCD Macrocycle", Bioorg. Med. Chem. Lett. 2004, 14, 1697–1702. doi: 10.1016/j.bmcl.2004.01.056.

10. Polt, R.;* Sames, D.; Chruma, J. "Glycoside Inhibitors: Synthesis of Enantiomerically Pure Aza-sugars from Schiff Base Amino Esters via Tandem Reduction-Alkenylation and Osmylation", J. Org. Chem. 1999, 64, 6147–6158. doi: 10.1021/jo9820115.

11. Chruma, J. J.; Sames, D.; Polt, R.* "General Method for the Synthesis of N-Methyl Amino Acids and N-Alkylated Amino Esters from O'Donnell's Schiff Base", Tetrahedron Lett. 1997, 38, 5085–5086. doi: 10.1016/S0040-4039(97)01132-5.