Publications

Publications at UVA (* indicates corresponding author, underline indicates undergraduate author)

BurkeTA2011

8. Burke, J. P.; Sabat, M.; Myers, W. H.; Chruma, J. J.* "Unexpected exo Selectivity for an Intramolecular Diels-Alder Reaction Involving a Doubly-Activated delta-Pentenolide Dienophile", Tetrahedron:Asymmetry 2011, 22, 31-35 [DOI:10.1016/j.tetasy.2010.12.018].

7. Burke, J. P.; Sabat, M.; Iovan, D. A.; Myers, W. H.; Chruma, J. J.* "Exploring the Original Proposed Biosynthesis of (+)-Symbioimine: Remote Exocyclic Stereocontrol in a Type I IMDA Reaction", Org. Lett. 2010, 12, 3192-3195 [DOI:10.1021/ol101141a] [PMID:20550217].

6. Bullock, G. C.; Delehanty, L. L; Talbot, A.-L.; Gonias, S. L.; Tong, W.-H.; Rouault, T. A; Dewar, B.; Macdonald, J. M.; Chruma, J. J.; Goldfarb, A. N.* "Iron Control of Erythroid Development by a Novel Aconitase-Associated Regulatory Pathway", Blood 2010, 116(1), 97-108 [DOI:10.1182/blood-2009-10-251496] [PMID:20407036].

5. Fields, W. H. and Chruma, J. J.* "Palladium-Catalyzed Decarboxylative Benzylation of Diphenylglycinate Imines", Org. Lett. 2010, 12(2), 316-319. [ doi: 10.1021/ol902651j] [PMID:20000671]

• Highlighted in SynFacts 2010, 4, 461

4. Chruma, J. J.*; Moon, S.-J.; Sanford, W. E., Jr. "Azaphilone alpha-Bromoacetates (AzalphaBs): Fluorescent Linchpin Reagents for the Inter- and Intramolecular Cross-Linkage of Primary Amines to Thiols", Lett. Org. Chem. 2009, 6, 367-371.

3.Yeagley, A. A.; Lowder, M. A.; Chruma, J. J.* "Tandem C–C Bond-Forming Processes: Interception of the Pd-Catalyzed Decarboxylative Allylation of Allyl Diphenylglycinate Imines with Activated Olefins", Org. Lett. 2009, 11(17), 4022-4025. [doi: 10.1021/ol901745x] [PMID: 19658425]

2. Fields, W. H.; Khan, A. K.; Sabat, M.; Chruma, J. J.* "One Pot Tandem Decarboxylative Allylation–Heck Cyclization of Allyl Diphenylglycinate Imines: Rapid Access to Polyfunctionalized 1-Aminoindanes", Org. Lett. 2008, 10(22), 5131-5134. [doi: 10.1021/ol801986m] [PMID: 18956870]

1. Yeagley, A. A. and Chruma, J. J.* "C–C Bond-Forming Reactions via Pd-Mediated Decarboxylative alpha-Imino Anion Generation", Org. Lett. 2007, 9(15), 2879–2882. [doi: 10.1021/ol071080f] [PMID: 17580888]

Publications prior to UVA

8. Chruma, J. J.; Liu, L.; Zhou, W.; Breslow, R.* "Hydrophobic and Electronic Factors in the Design of Dialkylglycine Decarboxylase Mimcs", Bioorg. Med. Chem. 2005, 13(20), 5873–5883. [doi: 10.1016/j.bmc.2005.05.019] [PMID:15713385]

7. Zhou, W.; Yerkes, N.; Chruma, J. J.; Liu, L.; Breslow, R.* "Chiral Polyamines from Reduction of Polypeptides: Asymmetric Pyridoxamine-Mediated Transaminations", Bioorg. Med. Chem. Lett. 2005, 15(5), 1351–1355. [doi: 10.1016/j.bmcl.2005.01.021] [PMID:15713385]

6. Liu, L.; Zhou, W.; Chruma, J.; Breslow, R.* "Tranamination Reactions with Multiple Turnovers Catalyzed by Hydrophobic Pyridoxamine Cofactors in the Presence of Polyethylene-imine Polymers. J. Am. Chem. Soc. 2004, 126(26), 8136–8137. [doi: 10.1021/ja048671a] [PMID: 15225053]

5. Si, Z.; Madani, N.; Cox, J. M.; Chruma, J. J.; Klein, J. C.; Schön, A.; Phan, N.; Wang, L.; Biorn, A. C.; Cocklin, S.; Chaiken, I.; Freire, E.; Smith, A. B., III; Sodroski, J. G.* "Small-Molecule Inhibitors of HIV-1 Entry Block Receptor-Induced Conformational Changes in the Viral Envelope Glycoproteins", Proc. Nat. Acad. Sci., USA, 2004, 101(14), 5036–5041. [doi: 10.1073/pnas.0307953101] [PMID: 15051887]

4. Madani, N.; Perdigoto, A. L.; Srinivasan, K.; Cox, J. M.; Chruma, J. J.; LaLonde, J.; Head, M.; Smith, A. B., III; Sodroski, J. G.* "Localized Changes in the gp120 Envelope Glycoprotein Confer Resistance to Human Immunodeficiency Virus Entry Inhibitors BMS-806 and #155", J. Virol. 2004, 78(7), 3742–3752. [doi: 10.1128/JVI.78.7.3742-3752.2004] [PMID: 15016894]

3. Smith, A. B., III;* Chruma, J. J.; Han, Q.; Barbosa, J. "Complestatin Synthetic Studies: The Effect of the Amino Acid Configuration on Peptide Backbone Conformation in the Common Western BCD Macrocycle", Bioorg. Med. Chem. Lett. 2004, 14(7), 1697–1702. [doi: 10.1016/j.bmcl.2004.01.056] [PMID: 15026053]

2. Polt, R.;* Sames, D.; Chruma, J. "Glycoside Inhibitors: Synthesis of Enantiomerically Pure Aza-sugars from Schiff Base Amino Esters via Tandem Reduction-Alkenylation and Osmylation", J. Org. Chem. 1999, 64, 6147–6158. [doi: 10.1021/jo9820115]

1. Chruma, J. J.; Sames, D.; Polt, R.* "General Method for the Synthesis of N-Methyl Amino Acids and N-Alkylated Amino Esters from O'Donnell's Schiff Base", Tetrahedron Lett. 1997, 38, 5085–5086. [doi: 10.1016/S0040-4039(97)01132-5]