University of Virginia
Department of Biochemistry and Molecular Genetics

Selected References

Bassett, E.A., DeNizio, J., Barnhart-Dailey, M.C., Panchenko, T., Sekulic, N., Rogers, D.J., Foltz, D.R., and Black B.E. (2012) HJURP Uses Distinct CENP-A Surfaces to Recognize and to Stabilize CENP-A/Histone H4 for Centromere Assembly. Dev.Cell 22;749 - 762

Foltz, D.R. and Stukenberg, P.T. A New histone at the Centromere? Cell 148: 394-396.

Silva, M.C., Bodor, D.L., Stellfox, M.E., Martins, N.M., Hochegger, H., Foltz, D.R., and Jansen, L.E. (2011) Cdk activity couples epigenetic centromere inheritance to cell cycle progression. Dev. Cell 22:52 – 63.

Mishra, P.K., Au, W.C., Choy, J.S., Kuich, P.H., Baker, R.E., Foltz, D.R., and Basrai, M.A. (2011) Misregulation of Scm3p/HJURP Causes Chromosome Instability in Saccharomyces cerevisiae and Human Cells. PLoS Genetics 7(9):e1002303.

Barnhart, M.C., Kuich, P.H, Stellfox, M.E., Ward, J.A., Bassett, E.A., Black, B.E., Foltz, D.R. (2011) HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore. J. Cell Biol. 194, 229-243.
**Perspective published in Science, 2012 Jan 20;335(6066):299-300

Black, B.E, Jansen L.E, Foltz, D.R., and Cleveland, D.W. (2010) Centromere Identity, Function, and Epigenetic Propagation across Cell Divisions. Cold Spring Harb Symp Quant Biol. 75: 403-418.

Bassett, E.A., Wood, S., Salimian, K.J., Ajith, S, Foltz, D.R., and Black B.E. (2010) Epigenetic Centromere Specification Directs Aurora B Accumulation but is Insufficient to Efficiently Correct Mitotic Errors. Journal Cell Biology, 190, 177-185.

Stukenberg, P.T., and Foltz, D.R. (2010) Kinetochores: orchestrating the minuet. Curr. Biol. 20, R522-525.

Foltz DR, Jansen LE, Bailey AO, Yates JR 3rd, Bassett EA, Wood S, Black BE, Cleveland DW. (2009) "Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP." Cell. May 1;137(3):472-84.    [PubMed]

Jansen LE, Black BE, Foltz DR, Cleveland DW. (2007) "Propagation of centromeric chromatin requires exit from mitosis." J Cell Biol. Mar 176:795-805. Epub 2007 Mar 5.     [PubMed]

Black BE, Jansen LE, Maddox PS, Foltz DR, Desai AB, Shah JV, Cleveland DW. (2007) "Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain." Mol Cell. Jan 25:309-22.     [PubMed]

Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR 3rd, Cleveland DW. (2006) "The human CENP-A centromeric nucleosome-associated complex." Nat Cell Biol. 8:458-69. Epub 2006 Apr 16.     [PubMed]

Black BE, Foltz DR, Chakravarthy S, Luger K, Woods VL Jr, Cleveland DW. (2004) "Structural determinants for generating centromeric chromatin." Nature. Jul 430(6999):578-82.     [PubMed]

Kops GJ, Foltz DR, Cleveland DW. (2004) "Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint." Proc Natl Acad Sci U S A. Jun 101(23):8699-704. Epub 2004 May 24.     [PubMed]