Fan, R., Kim, NG, and Gumbiner, B.M. (2013) Regulation of Hippo Pathway by Mitogenic Growth Factors via PI3-Kinase and Phosphoinositide-Dependent Kinase-1. Proc. Natl. Acad. Sci., Feb. 12; 110(7):2569-2574, PMCID: PMC3574943 [Available on 2013/8/12]. Abstract
Petrova, Y., Spano, MM., and Gumbiner, B.M. (2012) Conformational epitopes at cadherin calcium binding sites and p120-catenin phosphorylation regulate cell adhesion. Mol Biol Cell, 23(11): p. 2092-108, PMCID: PMC3364174. Abstract
Park, KS, Gumbiner, B.M., (2012) Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling, Devel. Biol., 366:232-243, PMCID: PMC3358420 [Available on 2013/6/15]. Abstract
Nam Hee Kim, Hyun Sil Kim, Nam-Gyun Kim, Inhan Lee, Hyung-Seok Choi, Xiao-Yan Li, Shi Eun Kang, So Young Cha, Joo Kyung Ryu, Jung Min Na, Changbum Park,1 Kunhong Kim, Sanghyuk Lee, Barry M. Gumbiner, Jong In Yook, Stephen J. Weiss (2011) p53 and microRNA-34 Are Suppressors of Canonical Wnt Signaling. Science Signaling, 4:197, 1-14.“PMC Journal – in Process”. Abstract
Yoder, M., and Gumbiner, B.M. (2011) Adhesion-independent specification and morphogenesis of the notochord and axial mesoderm by Axial Protocadherin (AXPC). Devel Dynamics, 240:11, 2495-2504, PMCID: PMC3197877. Abstract
Kim NG, Koh E, Chen X, Gumbiner B.M. (2011) E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components. Proc Natl Acad Sci., Jul 19;108(29):11930-5, PMCID: PMC3141988. Abstract
Park, KS, and Gumbiner, B.M. (2010) Cadherin 6B induces BMP signaling and de-epithelialization during the epithelial mesenchymal transition of the neural crest. Development, 137, 2691-2701, PMCID: PMC2910385. Abstract
Chen, X., Koh, E., Yoder, M., Gumbiner, B.M. (2009) A Protocadherin-Cadherin-FLRT3 complex controls cell adhesion and morphogenesis. PLoS One, 4(12): e8411, PMCID: PMC 2791867. Abstract
Kim, N.G., Xu, C., and Gumbiner,, B.M. (2009) Identification of targets of the Wnt pathway destruction complex in addition to β-catenin. Proc. Natl. Acad. Sci.,106:5165-5170, PMCID: 2663984. Abstract
Skoglund, P., Rolo, A., Chen, X., Gumbiner, B.M., and Keller, R., (2008) Convergence and extension at gastrulation require a myosin IIB-dependent cortical actin network. Development, 135:2435-2444, PMCID: PMC2735133. Abstract
Vonica, A. and Gumbiner, B.M. (2007) The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity. Devel. Biol., 312:90-102, PMCID: PMC2170525. Abstract
Chen, XJ, Molino, C., Liu, L., and Gumbiner, B.M. (2007) Structural elements necessary for oligomerization, trafficking and cell sorting function of Paraxial Protocadherin. J. Biol. Chem., 282:32128-32137. Abstract
Tsuiji, H., Xu, L., Schwartz, K., Gumbiner, B.M. (2007) Cadherin Conformations Associated with Dimerization and Adhesion. J. Biol. Chem., 282:12871-12882. Abstract
Perrais, M., Chen, X., Perez-Moreno, M., Gumbiner, B.M. (2007) E-Cadherin Homophilic Ligation Inhibits Cell Growth and Epidermal Growth Factor Receptor Signaling Independently of Other Cell Interactions. Mol Biol Cell, 18:2013-2025. Abstract
Mahadevaiyer, S., Xu, C., and Gumbiner, B.M. (2006) Characterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein. Bioch. Biophys. Acta Molecular Cell Research, 1773:120-130. Abstract
Chen, XJ and Gumbiner, B.M. (2006) Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity. J. Cell Biol., 174:301-313. Abstract
Qin, Y., Capaldo, C., Gumbiner, B. M. & Macara, I. G. (2005) The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. J Cell Biol. 171:1061-1071. Abstract
Gottardi, C.J. and Gumbiner, B.M. (2004) Distinct molecular forms of ß-catenin are targeted to adhesive or transcriptional complexes. J. Cell Biol., 167:339-350. Abstract
Gottardi, C.J. and Gumbiner, B.M. (2004) Role for ICAT (inhibitor of ß-catenin and TCF) in ß-catenin-dependent nuclear signaling and cadherin functions. Am. J. Physiol. Cell Physiol., 286:C747--C756. Abstract
Suh, Eun-Kyung, and Gumbiner, B. M. (2003) Translocation of beta-catenin into the nucleus independent of interactions with FG-rich Nucleoporins. Exptl. Cell Res., 290:447-456. Abstract
Wong, A. S. T. and Gumbiner, B. M. (2003) Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin, J. Cell Biol., 161:1191-1203. Abstract
Zhu, B., Chappuis-Flament, S., Wong, E., Jensen, I., Gumbiner, B.M., and Leckband, D.E. (2003) Functional Analysis of the Structural Basis of Homophilic Cadherin Adhesion. Biophys. J., 84:1-10. Abstract
Huen, A.C., Park, J.K., Godsel, L.M., Chen, X., Bannon, L.J., Amargo, E.V., Hudson, T.Y., Mongiu, A.K., Leigh, I.M., Kelsell, D.P., Gumbiner, B.M., and Green, K.J. (2002) Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate adhesive strength. J. Cell Biol., 159 1005-1017. Abstract
Vonica, A. and Gumbiner, B.M. (2002) Zygotic Wnt activity is required for Brachyury expression in the early Xenopus laevis embryo. Devel. Biol., 250:112-127. Abstract
Boggon, T. J. , Murray, J., Chappuis-Flament, S., Wong, E., Gumbiner, B.M., and Shapiro, L. (2002) C-Cadherin ectodomain structure and implications for cell adhesion mechanisms. Science, 296:1308-1313. Abstract
Niessen, C.M. and Gumbiner, B.M. (2002) Cadherin mediated cell sorting not determined by binding or adhesion specificity. J. Cell Biol. 156:389-400. Abstract
Noren, N.K., Niessen, C.M. , Gumbiner, B.M. , and Burridge, K. (2001) Cadherin Engagement Regulates Rho family GTPases. J. Biol. Chem. 276:33305-33308. Abstract
Chappuis-Flament, S., Wong, E., Hicks, L. D., Kay, C. M., and Gumbiner, B. M. (2001). Multiple cadherin extracellular repeats mediate homophilic binding and adhesion. J. Cell Biol., 154:231-243. Abstract
Gottardi, Cara J., Wong Ellen, and Gumbiner, B.M. (2001) E-cadherin suppresses cellular transformation by inhibiting ß-catenin signaling in an adhesion-independent manner. J. Cell Biol., 153: 1049–1059. Abstract
Reinacher-Schick, A. and Gumbiner, B.M. (2001) Apical membrane localization of the APC tumor suppressor protein and subcellular distribution of the ß-catenin destruction complex in polarized epithelial cells. J. Cell Biol., 152: 491-502. Abstract
Sivasankar, S., Gumbiner, B., and Leckband, D. (2001) Direct measurements of multiple adhesive alignments and unbinding trajectories between cadherin extracellular domains. Biophys. J., 80: 1758-1768. Abstract
Guger, K.A. and Gumbiner. B.M. (2000) A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels. Dev. Biol., 223:441-448. Abstract
Vonica, A., W. Weng, B.M. Gumbiner, and J.M. Venuti. 2000. TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis. Dev Biol. 217:230-243. Abstract
Nelson, R.W. and Gumbiner, B.M. (1999) A cell-free assay system for ß-catenin signaling that recapitulates direct inductive events in the early Xenopus embryo. J. Cell Biol., 147:367-374. Abstract
Sivasankar, S., Brieher, W., Lavrik, N., Gumbiner, B.M., Leckband, D. (1999) Direct Molecular Force Measurements of Multiple Adhesive Interactions Between Cadherin Ectodomains, Proc. Natl. Acad. Sci. USA, 96:11820-11824. Abstract
Lecuit, M., S. Dramsi, C. Gottardi, M. Fedor-Chaiken, B. Gumbiner, and P. Cossart. (1999) A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes. EMBO J. 18:3956-3963. Abstract
Zhong, Y, Brieher, W.M., and Gumbiner, B.M. (1999) Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody. J. Cell Biol., 144:351-359. Abstract
Yap, A.S., Niessen, C.M., and Gumbiner, B.M. (1998) The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening and interaction with p120ctn. J. Cell Biol., 141:779-790. Abstract
Nelson, R.W. and Gumbiner, B.M. (1998) ß-Catenin directly induces expression of the siamois gene, and can initiate signaling indirectly via a membrane-tethered form. Annals of the New York Academy of Sciences, Morphogenesis: Cellular Interactions, 857:86-98. Abstract
Fagotto, F., Glück, U., and Gumbiner, B.M. (1998) Nuclear localization signal-independent- and importin/karyopherin-independent nuclear import of ß-catenin. Current Biology, 8:181-190. Abstract
Sehgal, R.N.M., Gumbiner, B.M., and Reichardt, L.F. (1997) Antagonism of cell adhesion by an alpha-catenin mutant, and of the Wnt-signaling pathway by alpha-catenin in Xenopus embryos. J. Cell Biol. 139:1033-1046. Abstract
Zeng, L., Fagotto, F., Zhang, T., Hsu, W., Vasicek, T.J., Perry, W.L. III, Lee, J.J., Tilghman, S.M., Gumbiner, B.M., and Costantini, F. (1997) The mouse Fused locus encodes Axin, an inhibitor or the Wnt signaling pathway that regulates embryonic axis formation. Cell, 90:181-192. Abstract
Yap, A.S., Brieher, W.M., Pruschy, M., and Gumbiner, B.M. (1997) Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function. Current Biology, 7:308–315. Abstract
Vleminckx, K., Wong, E., Guger, K., Rubinfeld, B., Polakis, P. and Gumbiner, B.M. (1997) The APC tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis. J. Cell Biol., 136:411-420. Abstract
Fagotto, F., Guger, K., and Gumbiner, B.M. (1997) Induction of Siamois in the primary dorsalizing center in Xenopus by the Wnt/GSK/ß-catenin signaling pathway, but not by Vg1, Activin, or Noggin. Development, 124:453-460. Abstract
Wong, V. and Gumbiner, B.M. (1997) A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J. Cell Biol., 136, 399-409. Abstract
Brieher, W.M., Yap, A.S., and Gumbiner, B.M. (1996) Lateral dimerization is required for the homophilic binding activity of C-cadherin. J. Cell Biol., 135:487-496. Abstract
Witcher, L.L., Collins, R., Puttagunta, S., Mechanic, S., Munson, M., Gumbiner, B. and Cowin, P. (1996) Desmosomal cadherin binding domains of plakoglobin. J. Biol. Chem., 271, 10904-10909. Abstract
Fagotto, F., Funayama, N., Glück, U. and Barry M. Gumbiner (1996) Binding to cadherins antagonizes the signaling activity of ß-catenin during axis formation in Xenopus. J. Cell Biol., 132, 1105-1114. Abstract
Guger, K. and Gumbiner, B.M. (1995) ß-catenin has Wnt-like activity and mimics the Nieuwkoop signaling center in Xenopus dorsal-ventral patterning. Devel. Biol., 172, 115-125. Abstract
Lee, C-H. and Gumbiner, B.M. (1995) Disruption of gastrulation movements in Xenopus by a dominant negative mutant for C-cadherin. Devel. Biol., 171, 363-373. Abstract
Funayama, N., Fagotto, F., McCrea, P., and Gumbiner, B.M. (1995) Embryonic axis induction by the armadillo repeat domain of ß-catenin: evidence for intracellular signalling. J. Cell Biol., 128, 959-968. Abstract
Heasman, J., Crawford, A., Goldstone, Garner-Hamrick, P., Gumbiner, B.M., K., McCrea, P., Kintner, C., Yoshida Noro, Y., and Wylie, C. (1994) Overexpression of cadherins and underexpression of ß-catenin inhibit dorsal mesoderm induction in early Xenopus embryos. Cell, 79, 791-803. Abstract
Fagotto, F. and Gumbiner, B.M. (1994) ß-catenin localization during Xenopus embryogenesis: accumulation at tissue and somite boundaries. Development, 120, 3667-3679. Abstract
Brieher, W.M. and Gumbiner, B.M. (1994) Regulation of cadherin function during activin induced morphogenesis of Xenopus animal caps. J. Cell Biol. 126, 519-527. Abstract
Levine, E., Lee, C.H., Kintner, C., and Gumbiner, B.M. (1994) Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant. Development, 120, 901-910. Abstract
McCrea, P.D., Brieher, W.M., and Gumbiner, B.M. (1993) Induction of a secondary body axis in Xenopus by antibodies to beta-catenin. J. Cell Biol. 123, 477-484. Abstract
Peifer, M., McCrea, P., Green, K.J., Wieschaus, E., and Gumbiner, B. (1992) The vertebrate adhesive junction proteins ß-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties. J. Cell Biol. 118, 681-691. Abstract
McCrea, P., Turck, C.W., and Gumbiner, B. (1991) A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science, 254, 1359-1361. Abstract
Gumbiner, B., Lowenkopf, T., and Apatira, D. (1991) Identification of a 160 kD polypeptide that binds to the tight junction protein ZO-1. Proc. Natl. Acad. Sci. USA, 88, 3460-3464. Abstract
Levi, G., Gumbiner, B. and Thiery, J.-P. (1991) The distribution of E-cadherin during Xenopus laevis development. Development, 111, 159-169. Abstract
McCrea, P. and Gumbiner, B. ( 1991) Purification of a 92kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin) ; characterization and extractability of the protein complex from the cell cytostructure. J. Biol. Chem., 266, 4514-4520. Abstract
Choi, Y.S., Sehgal, R., McCrea, P. and Gumbiner, B. (1990) A cadherin-like protein in eggs and cleaving embryos of Xenopus laevis is expressed in oocytes in response to progesterone. J. Cell Biol. 110, 1575-1582. Abstract
Choi, Y.S. and Gumbiner, B. (1989) Expression of cell adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm. J. Cell Biol. 108, 2449-2458. Abstract
Gumbiner, B., Stevenson, B. and Grimaldi, A. (1988) The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J. Cell Biol. 107, 1575-1587. Abstract
Finlay, B.B., Gumbiner, B., and Falkow, S. (1988) Penetration of Salmonella through a polarized MDCK epithelial cell monolayer. J. Cell Biol. 107, 221-230. Abstract
van Meer, G., Gumbiner, B. and Simons, K. (1986) The tight junction does not allow lipid molecules to diffuse from one epithelial cell to the next. Nature 322, 639-641. Abstract
Gumbiner, B. and Simons, K. (1986) A functional assay for proteins involved in establishing an epithelial occluding barrier: Identification of a uvomorulin-like polypeptide. J. Cell Biol. 102, 457-468. Abstract
Moore, H.P., Gumbiner, B. and Kelly, R. (1983) A subclass of proteins and sulfated macromolecules secreted by AtT-20 (mouse pituitary tumor) cells is sorted with Adrenocorticotropin into dense secretory granules. J. Cell Biol. 97, 810-817. Abstract
Moore, H.P., Gumbiner, B. and Kelly, R. (1983) Chloroquine diverts ACTH from a regulated to a constitutive secretory pathway in AtT-20 cells. Nature 302, 434-436. Abstract
Gumbiner, B. and Kelly, R. (1982) Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells. Cell 28, 51-59. Abstract
Gumbiner, B. and Kelly, R. (1981) Secretory granules of an anterior pituitary cell line, AtT-20, contain only mature forms of corticotropin and ß-lipotropin. Proc. Natl. Acad. Sci. USA 78, 318-322. Abstract
Xu, C., Kim N.G., Gumbiner, B.M. (2009) Regulation of protein stability by GSK3 mediated phosphorylation, Cell Cycle, Vol. 8, Issue 24:4032-4039. Abstract
Chen, X., Gumbiner, B.M. (2006) Crosstalk between different adhesion molecules. Curr. Opin. in Cell Biol., 18:1-7. Abstract
Gumbiner, B.M. (2005) Regulation of cadherin-mediated adhesion in morphogenesis. Nature Reviews Molecular Cell Biology, 6:622-634. Abstract
Gumbiner, B.M. (2005) Coordinate gene regulation by two different catenins. Devel. Cell 8, 1-2. Abstract
Gottardi, C.J. and Gumbiner, B.M. (2001) Adhesion signaling: How ß-catenin interacts with its partners. Current Biology, 11:19:R792-R794. Abstract
Gumbiner, B.M. (2000) Regulation of cadherin adhesive activity. J. Cell Biol., 148, 399-403. Abstract
Gottardi, C.J.., Niessen, C.M., and Gumbiner, B.M (2001) The Adherens Junction. Chapter 8. In: Cell Adhesion, ed. by Mary Beckerlie, The Frontiers in Molecular Biology Series, eds. B.D. Hames and D.M. Glover, Oxford University Press., pgs. 259-287.
Gumbiner, B.M. (1998) Propagation and localization of Wnt signaling. Curr. Opin. Genetics and Devel., Vol. 8 No. 4: 430-435. Abstract
Yap, A.S., Brieher, W.M., and Gumbiner, B.M. (1997) Molecular and functional analysis of cadherin-based adherens junctions. Ann. Rev. Cell and Dev. Biol. 13:119-146. Abstract
Gumbiner, B.M. (1997) Carcinogenesis: A balance between ß-catenin and APC. Current Biology, 7, R443-R446. Abstract
Fagotto, F. and Gumbiner, B.M. (1996) Cell contact-dependent signaling. Devel. Biol. 180, 445-454. Abstract
Gumbiner, B.M. (1996) Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell, 84, 345-357. Abstract
Patel, D.J., and B.M. Gumbiner (1995) Cell-cell recognition. Zipping together a cell adhesion interface. Nature. 374:306-307. Abstract
Gumbiner, B.M. (1995) Signal Transduction by ß-catenin. Curr. Opin. Cell Biol. 7, 634-640. Abstract
Gumbiner, B.M. (1993) Breaking through the tight junction barrier. J. Cell Biol. 123, 1631-1633. Abstract
Gumbiner, B.M. and McCrea, P.D. (1993) Catenins as mediators of the cytoplasmic functions of cadherins. J.Cell Sci. Supplement 17, 155-158. Abstract
Gumbiner, B.M. (1993) Proteins associated with the cytoplasmic surface of adhesion molecules. Neuron, 11, 1-20. Abstract
Gumbiner, B.M. (1992) Epithelial Morphogenesis. Cell 69, 1-20. Abstract
Gumbiner, B. (1991) Membrane glycoprotein choreography. Current Biology. vol.1, no. 4., 271-273. Abstract
Gumbiner, B. (1991) Cell adhesion molecules in epithelia. In: Tight Junctions. ed. by M. Cereijido, CRC Press, Boca Raton, Florida, pp 91-104.
Gumbiner, B. (1990) Generation and maintenance of cell polarity. Current Opinions in Cell Biology. Extracellular matrix and cell-cell contact, 2, 881-887. Abstract
Gumbiner, B. (1988) A family of calcium-dependent adhesion molecules. Trends in Biochem. Sci., 13, 75-76. Abstract
Gumbiner, B. (1987) The structure, biochemistry, and assembly of epithelial tight junctions. Am. J. Physiol.: Cell Physiol. 253, C749 - C758. Abstract
Gumbiner, B. (1986) A Ca2+-triggered molecular switch in neurons. Trends in Biochem. Sci. 11, 308-309.
Gumbiner, B. and Simons, K. (1986) The role uvomorulin in the formation of epithelial occluding junctions. In: Junctional Complexes of Epithelial Cell "S", Ciba Foundation Symposium 125.G. Bock and S. Clark, editors. John Wiley and Sons Ltd., Chichester.pp 168-186. Abstract
Gumbiner, B. and Louvard, D. (1985) Localized barriers in the plasma membrane: a common way to form domains. Trends in Biochem.Sci. 10, 435-438.