Dr. Brett R. Blackman
Assistant Professor of Biomedical Engineering
PhD, University of Pennsylvania, 1998
bblackman@virginia.edu
Dr. Blackman earned a BS in Mechanical Engineering from Drexel University in 1994. He earned a PhD in Bioengineering at the University of Pennsylvania (1998) in Dr. Lawrence Thibault’s Lab, where his graduate work studied the effects of mechanical forces (i.e., shear stress) on endothelial cell intracellular calcium response in the context of vascular injury and atherosclerosis. Dr. Blackman then completed a postdoctoral fellowship at Boston’s Brigham and Women’s Hospital/Harvard Medical School in Dr. Michael Gimbrone’s Lab. There he developed the first in vitro model to stimulate human endothelial cells to human inspired hemodynamic flow patterns. Dr. Blackman joined the faculty at Virginia in 2002. The Blackman lab uses innovative monoculture and co-culture models to investigate the early mechanisms regulating endothelial and smooth muscle cell phenotype in human atherosclerosis and the critically relevant role regional hemodynamic shear stresses have in regulating this disease.