Chemical Engineering Department SEAS Home Kyle Lampe Research group


Publications:

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  1. DB Unal, SR Caliari, KJ Lampe, "Engineering Biomaterial Microenvironments to Promote Myelination in the Central Nervous System," Brain Research Bulletin (2019, in press. link
  2. JD Tang, Roloson EB, Amelung CD, KJ Lampe, "Rapidly Assembling Pentapeptides for Injectable Delivery (RAPID) Hydrogels as Cytoprotective Cell Carriers," ACS Biomater. Sci. Eng. 5: 2117-2121 (2019) . link
  3. E Meco, KJ Lampe, "Impact of Elastin-like Protein Temperature Transition on PEG-ELP Hybrid Hydrogel Properties," Biomacromolecules, (2019) in press. link
  4. JD Tang, C Mura, KJ Lampe, "A stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering," J. Am. Chem. Soc., 141: 4886-4899 (2019). link
  5. CM Madl, BL LeSavage, RE Dewi, KJ Lampe & SC Heilshorn, "Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels," Advanced Science, 6: 1801716 (2019). link
  6. JD Tang, SR Caliari, KJ Lampe, "Temperature-dependent complex coacervation of engineered elastin-like polypeptide and hyaluronic acid polyelectrolytes," Biomacromolecules, 19: 3925-3935 (2018). link
  7. MR Pinezich, LN Russell, NP Murphy, KJ Lampe, “Encapsulated oligodendrocyte precursor cell fate is dependent on PDGF-AA release kinetics in a 3D microparticle-hydrogel drug delivery system,” Journal of Biomedical Materials Research-A, 106: 2402-2411 (2018). (link)
  8. E Meco, KJ Lampe, "Microscale architecture in biomaterial scaffolds for spatial control of neural cell behavior," Frontiers in Materials, 5: 2 (2018). link
  9. JD Tang, KJ Lampe, “From de novo peptides to native proteins: advancements in biomaterial scaffolds toward acute ischemic stroke repair,” Biomedical Materials, 13: 3 (2018). link
  10. CM Madl, BL LeSavage, RE Dewi, CB Dinh, RS Stowers, M Khariton, KJ Lampe, DNguyen, O Chaudhuri, AEnejder & SC Heilshorn, "Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling," Nature Materials 16, 1233-1242 (2017). (link)
  11. NP Murphy, KJ Lampe, “Fabricating PLGA microparticles with high loads of the small molecule antioxidant N-acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress,” Biotechnology and Bioengineering, 115: 246-256 (2017). link
  12. LN Russell, KJ Lampe, "Oligodendrocyte Precursor Cell Viability, Proliferation, and Morphology is Dependent on Mesh Size and Storage Modulus in 3D Poly(ethylene glycol) Based Hydrogels," ACS Biomater. Sci. Eng. (2017). link
  13. JD Tang, CE McAnany, C Mura, KJ Lampe, "Toward a Designable Extracellular Matrix: Molecular Dynamics Simulations of an Engineered Laminin-Mimetic, Elastin-Like Fusion Protein," Biomacromolecules, 17: 3222–3233 (2016). link
  14. LN Russell, KJ Lampe, “Engineering biomaterials to influence oligodendroglial growth, maturation, and myelin production,” Journal of Cells, Tissues, and Organs, 202: 85-101 (2016).link
  15. NP Murphy, KJ Lampe, “Mimicking biological phenomena in hydrogel-based biomaterials to promote dynamic cellular responses,” Journal of Materials Chemistry B, 3: 7867-7880 (2015). (link)
  16. NH Romano, KJ Lampe, H Xu, MM Ferreira, SC Heilshorn “Microfluidic gradients reveal enhanced neurite outgrowth but impaired guidance within 3D matrices with high integrin ligand densities,” Small, 11: 722-730 (2015). (link)
  17. KJ Lampe, AL Antaris, SC Heilshorn “Design of 3D engineered protein hydrogels for tailored control of neurite growth,” Acta Biomaterialia, 9: 5590-5599 (2013). (link)
  18. C Chung, KJ Lampe, SC Heilshorn “Tetrakis (hydroxyl methyl) phosphonium chloride as a covalent crosslinking agent for cell encapsulation within protein-based hydrogels,” Biomacromolecules, 13: 3912-3916 (2012). (link)
  19. KJ Lampe, SC Heilshorn “Building stem cell niches from the molecule up through engineered peptide materials,” Invited review, Neuroscience Letters, 519: 138-146 (2012). (link)
  20. BA Aguado, W Mulyasasmita, J Su, KJ Lampe, SC Heilshorn, “Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers,” Tissue Engineering Part A, 18: 806-815 (2012). (link)
  21. ER Aurand, KJ Lampe, KB Bjugstad, “Defining and Designing Polymers and Hydrogels for Neural Tissue Engineering,” Neuroscience Research, 72: 199-213 (2012). (link)
  22. KJ Lampe, DS Kern, MJ Mahoney, KB Bjugstad, “The administration of BDNF and GDNF to the brain via PLGA microparticles patterned within a degradable PEG-based hydrogel: protein distribution and the glial response,” Journal of Biomedical Materials Research Part A, 96A: 595-607 (2011). (link)
  23. KB Bjugstad, KJ Lampe, DS Kern, MJ Mahoney, “Biocompatibility of poly(ethylene glycol)-based hydrogels in the brain: An analysis of the glial response across space and time,” Journal of Biomedical Materials Research Part A, 95A:79-91 (2010). (link)
  24. KJ Lampe*, RG Mooney*, KB Bjugstad, MJ Mahoney, “Effect of macromer weight percent on neural cell growth in 2D and 3D nondegradable PEG hydrogel culture,” Journal of Biomedical Materials Research Part A: 94A, 1162-1171 (2010). (link) *contributed equally to this work
  25. KJ Lampe, KB Bjugstad, MJ Mahoney, “Impact of degradable macromer content in a poly(ethylene glycol) hydrogel on neural cell metabolic activity, redox state, proliferation, and differentiation,” Tissue Engineering Part A, 16:1857-1866 (2010). (link)
  26. KJ Lampe, RM Namba, TR Silverman, KB Bjugstad, MJ Mahoney, “Impact of lactic acid on cell proliferation and free radical-induced cell death in monolayer cultures of neural precursor cells,” Biotechnology and Bioengineering, 103:1214-1223 (2009). (link)
  27. KB Bjugstad, DE Redmond, KJ Lampe, DS Kern, JR Sladek Jr, MJ Mahoney, “Biocompatibility of PEG-Based Hydrogels in Primate Brain,” Cell Transplantation, 17:409-417 (2008). (link)