Tissue engineering scaffolds fabricated from nanofibers are gaining importance due to their unique similarity to extracellular matrices, high porosity, and ease of fabrication. Also the nanofibers have an advantage of enormous surface area due to very high length to diameter ratio of the fibers. A very elegant process to make the nanofiber scaffolds is by subjecting the polymer solution or melts to very high potential difference. A variety of parameters such concentration, melt viscosity, potential difference etc. can be optimized to obtain desired diameter and morphology of the resultant nanofibers. Further these nanofibers can also be formed to three dimensional scaffolds that can be used as the scaffold for tissue engineering.

In our laboratory, we are investigating the different ways to fabricate two and three dimensional nanofibers from a variety of biodegradable and non biodegradable polymers that could be used for a various biomedical applications.