Graduate Genetics (BIMS 808)

Mammalian genetics (non-human)

(mostly mouse)

Sonia Pearson-White

Department of Microbiology,

and Biochemistry and Molecular Genetics

email questions to Sonia

This section of the course will have 6 lectures. This homepage contains the outline of the material I will cover.

Figures from Strachan and Read are also available at the website

March 29, 2004 March 31, 2004 April 2, 2004 April 5, 2004 April 7, 2004 April 9, 2004

Lecture 1,

Triplet repeat diseases, Mouse genome, Mouse-human comparisons, inbred strains

Lecture 2,

X inactivation and imprinting

Lecture 3,

Directed gene expression or ablation, transgenic mice, gain-of-function approaches

Lecture 4,

Gene replacement techniques, Cre-lox tissue specific targeting

Lecture 5,

More Gene replacement, findings

Lecture 6,

Stem cells,

Cloning, reproductive and therapeutic


2004 Reading list for 808, by topic

or, Alphabetical Reading list for 2008



N.B. Figures print well using Internet Explorer, but expand too much using Netscape, taking over the whole page.


as announced by Dan Burke, April 28 at 9 am