Ski knockout andwildtype newborn mice

from Berk, M., S. Y. Desai, H. C. Heyman, and C. Colmenares. 1997. Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development. Genes & Development 11:2029-2039.

(A) wild type,(B) ski null,(C) ski null with exencephaly, (D) craniofacial clefting sometimes seen in ski null

ski -/- on left and wild type on right. Note the reduced skull in the knockout.

Pearson-White lab, unpublished

from Berk, M., S. Y. Desai, H. C. Heyman, and C. Colmenares. 1997. Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development. Genes & Development 11:2029-2039.