Raghu Mirmira, M.D., Ph.D.,
received a B.A. in chemistry, a Ph.D. in molecular biology, and an M.D.
from the University of Chicago. In 2000, he joined the faculty at the
University of Virginia as an assistant professor in the Division of
Endocrinology and Metabolism. Prior to coming to UVa, he did his
residency at the University of California, San Francisco, where he also
held various clinical and research positions.
The Mirmira laboratory is
interested in understanding the molecular mechanisms that are relevant
to the formation of islet cells within the pancreas. The primary focus
of the lab is to study transcription factors (TFs), which can be
thought of as "master switches" that regulate the rate of transcription
of a variety of genes that are involved in developmental processes. In
the long term, the laboratory is involved in looking at ways to cure
diabetes by converting potential precursor cells into insulin-producing
beta [islet] cells by "genetic reprogramming."