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synthesis and molecular structure of Zn(II)
and Cd(II) complexes with nucleic acid components
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| molecular structure of a platinated G.GC DNA triplex | |
| ab initio quantum chemical study of metal-modified noncomplementary DNA base pairs | |
| molecular dynamics of purine.purine-pyrimidine DNA triplexes | |
| NMR spectroscopy of Cd(II) complexes with DNA fragments | |
| molecular modeling of acetylcholinesterase
inhibitors |
Former Undergraduate Research Students:
| Andrea Benvin | 2000 David Harrison III Award for Undergraduate Research |
| Jenafer Evans | UVA Chemistry Department's Award for Excellence in Research |
| Beau Gardner | |
| Theresa Hilley | UVA Chemistry Department's Award for Excellence in Research |
| Zachary Hodgins | |
| Christine Ingersoll | |
| Michael Keller | 2002 David Harrison III Award for Undergraduate Research; GlaxoSmithKline Summer 2002 Research Fellowship |
| Evan Kransdorf | Summer Undergraduate Research Fellowship from the Dean of the College of Arts and Sciences, UVA |
| Chetan Maingi | |
| Molly McClain | |
| Jenny Owens | |
| Frances Rees | |
| Maureen Shevlin | |
| DeCarlos Taylor | Summer Undergraduate Research Fellowship from the Dean of the College of Arts and Sciences, UVA |
| Reo Lawrence Ivan Baxter Anne Doody Rebecca Rostand DeCarlos Taylor Amanda Mower Teresa Urban |
Evan Kransdorf Noelle Dwarzski Sarah Sutter Christopher Bender Alicia Douglas Martina Vondrova Sara Higgins |
Marilise Hyacinth Michael Keller Casey Micale |
Our current undergraduate research group consists of nine students. Their projects, although quite diverse, do have one subject in common; we concentrate on biophysical and bioinorganic chemistry of nucleic acids. All available research techniques, including the synthesis of model compounds, X-ray crystallography, NMR spectroscopy and computational chemistry, are applied.

Members of the team (from left to right): Sooin Lee, Stan Parish, Greg Broughton, Alice Hang, Sang Park, Dr. Michal Sabat,
Janeen Oberlander, Scott Geyer, Catherine Balchunas, and Jenny Owens.
Catherine Balchunas. Cadmium
and the DNA Repair System.
Gregory Broughton, Recipient of
the 2001 David Harrison III Award for Undergraduate Research. Molecular
Properties of CdS and CdSe Semiconductor Nanoparticles Crosslinked by DNA.
Scott Geyer. Metal Ions in (GA.TC)n
DNA Sequences.
Alice Hang. NMR Studies of DNA
Hairpins.
Sooin Lee. Applications of Metal-Modified
Nucleotides.
Janeen Oberlander. Cadmium and
the DNA Repair System.
Stan Parish. Applications of
Metal-Modified Nucleotides.
Sang Park. Crystallization and
Structure of Metal-Containing DNA Fragments.

A typical summer day at the Molecular Structure Laboratory. REU 2002 students (left to right): Michael Keller, Sara Higgins, Marilise Hyacinth, and Casey Micale. Photo: courtesy of Prof. Demas.
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Left: Off to work! Casey, Marilise, and Sara are rushing to start their research. Right: Mike is just about to give the best talk of his life*.
The last day of summer research. Unfortunately, the request for the prom dress was largely ignored.
(Molecular Structure Laboratory Homepage)
* Written under protest. MDK