Undergraduate Research


Undergraduate research is a very important activity in our laboratory. Over the years, several interesting projects have been developed by undergraduate researchers, including:

 synthesis and molecular structure of Zn(II) and Cd(II) complexes with nucleic acid components

 molecular structure of a platinated G.GC DNA triplex
 ab initio quantum chemical study of metal-modified noncomplementary DNA base pairs
 molecular dynamics of purine.purine-pyrimidine DNA triplexes
 NMR spectroscopy of Cd(II) complexes with DNA fragments
 molecular modeling of acetylcholinesterase inhibitors

Former Undergraduate Research Students:

Andrea Benvin 2000 David Harrison III Award for Undergraduate Research
Jenafer Evans UVA Chemistry Department's Award for Excellence in Research
Beau Gardner  
Theresa Hilley UVA Chemistry Department's Award for Excellence in Research
Zachary Hodgins
Christine Ingersoll
Michael Keller 2002 David Harrison III Award for Undergraduate Research; GlaxoSmithKline Summer 2002 Research Fellowship
Evan Kransdorf Summer Undergraduate Research Fellowship from the Dean of the College of Arts and Sciences, UVA
Chetan Maingi  
Molly McClain
Jenny Owens
Frances Rees
Maureen Shevlin
DeCarlos Taylor Summer Undergraduate Research Fellowship from the Dean of the College of Arts and Sciences, UVA

Students Participating in Summer REU Programs (1994-2002):

Reo Lawrence

Ivan Baxter

Anne Doody

Rebecca Rostand

DeCarlos Taylor

Amanda Mower

Teresa Urban

Evan Kransdorf

Noelle Dwarzski

Sarah Sutter

Christopher Bender

Alicia Douglas

Martina Vondrova

Sara Higgins

Marilise Hyacinth

Michael Keller

Casey Micale


Current Research Group:

Our current undergraduate research group consists of nine students. Their projects, although quite diverse, do have one subject in common; we concentrate on biophysical and bioinorganic chemistry of nucleic acids. All available research techniques, including the synthesis of model compounds, X-ray crystallography, NMR spectroscopy and computational chemistry, are applied.

 

Members of the team (from left to right): Sooin Lee, Stan Parish, Greg Broughton, Alice Hang, Sang Park, Dr. Michal Sabat,

Janeen Oberlander, Scott Geyer, Catherine Balchunas, and Jenny Owens.

 Catherine Balchunas. Cadmium and the DNA Repair System.

 Gregory Broughton, Recipient of the 2001 David Harrison III Award for Undergraduate Research. Molecular Properties of CdS and CdSe Semiconductor Nanoparticles Crosslinked by DNA.

 Scott Geyer. Metal Ions in (GA.TC)n DNA Sequences.

 Alice Hang. NMR Studies of DNA Hairpins.

 Sooin Lee. Applications of Metal-Modified Nucleotides.

 Janeen Oberlander. Cadmium and the DNA Repair System.

 Stan Parish. Applications of Metal-Modified Nucleotides.

 Sang Park. Crystallization and Structure of Metal-Containing DNA Fragments.

 

 

A typical summer day at the Molecular Structure Laboratory. REU 2002 students (left to right): Michael Keller, Sara Higgins, Marilise Hyacinth, and Casey Micale. Photo: courtesy of Prof. Demas.

 

Left: Off to work! Casey, Marilise, and Sara are rushing to start their research. Right: Mike is just about to give the best talk of his life*.

The last day of summer research. Unfortunately, the request for the prom dress was largely ignored.

(Molecular Structure Laboratory Homepage)

* Written under protest. MDK