Protein Chromatography
Engineering Fundamentals and Measurements for Process Development and Scale-up

Course Director: Prof. Giorgio Carta

Chromatography is an indispensable tool for the industrial production of proteins and other biotechnology products. Process development usually begins with laboratory scale scouting tests to determine suitable stationary phases and operating conditions. If successful, the next step is the optimization of operating conditions and scale-up. The aim of this course is to provide insight in the theory of chromatography, an understanding of fundamental engineering scale-up relationships, and an overview of methodologies for the experimental measurement of scale-up parameters and of optimization tools.

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