Alex Liqi Lai, Ph.D., Research Associate
|
|
Hometown: Guangzhou, China B.S.: Fudan University, 1997 M.S.: National University of Singapore, 2002 Ph.D.: University of Virginia, 2007 |
Publications:
Tamm, L.K., Lai, A.L., Li Y..(2007) Combined NMR and EPR spectroscopy to determine structures of viral fusion domains in membranes. Bioch. Biop. Acta . 1768: 3052-3060 (Full text in PDF)
Lai, A.L. and Tamm, L.K. (2007) Locking the kink in the influenza hemagglutinin fusion domain structure. J. Biol. Chem. 282:23946-23956. (Full text in PDF) (Supplement)
Lai AL, Park H, White JM, Tamm LK. (2006). Fusion Peptide of influenza hemagglutinin requires a fixed angle boomerang structure for activity. J Biol Chem. 2006 Mar 3;281(9):5760-70 (Full text in PDF)
Li, Y., Han,X., Lai, A.LQ, Bushweller J.H., Cafiso D.S., Tamm L.K. (2005). Membrane Structures of the Hemifusion-Inducing Fusion Peptide Mutant G1S and the Fusion Blocking Mutant G1V of Influenza Virus Hemagglutinin Suggest a mechanism for Pore Opening in Membrane Fusion. Journal of Virology Vol.79 No.18: 12065-12076. (Full text in PDF)
Lai, A. L., Li, Y., Tamm, L. K. (2005). Interplay of Proteins and Lipids in Virus Entry by Membrane Fusion. In Tamm, L. K. (Eds.) Protein-Lipid Interactions: From Membrane Domains to Cellular Networks. WILEY-VCH Verlag GmbH & Co. KGaA. 279-306.
Bai, J., Lai, A. L., Yeo, H. C., Goh, B. C., Tan, T. M. (2004). Multidrug Resistance Protein 4 (MRP4/ABCC4) Mediates Efflux of Bimane-Glutathione. Int. J. Biochem. Cell Biol. 36(2):247-57.
VanLoock, M. S., Yu, X., Yang, S., Lai, A. L., Low, C., Campbell, M. J., Egelman, E. H. (2003). ATP-Mediated Conformational Changes in the RecA Filament. Structure. 11(2): 187-96.
Lai, A. L., Tan, T. M. (2002). Role of Glutathione in the Multidrug Resistance Protein 4 (MRP4/ABCC4)-Mediated Efflux of cAMP and Resistance to Purine Analogues. Biochem J. 2002 Feb 1;361(Pt 3):497-503.
Tamm, L.K., X. Han, Y. Li, and A.L. Lai (2002). Structure and function of membrane fusion peptides. (Review) Biopolymers (Peptide Science). 66: 249-260. (Full text in PDF)
