Dan Theodorescu MD PhD

University of Virginia

Charlottesville, VA

Professor of Urology

Professor of Molecular Physiology

Paul Mellon Chair in Urologic Oncology

 

 

Last update:

08/27/2006

 

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Dr. Dan Theodorescu

 

 

 

MEDLINE INDEXED PUBLICATIONS as of 7/11/06

(For complete record, go to PUBMED)

 

1.       Blair, G.K., Filler, R.M., and Theodorescu, D. 1987.Neonatal pharyngoesophageal perforation mimicking esophageal atresia: clues to diagnosis. J Pediatr Surg, 22:770-774

 

 2.       Adams, C., Theodorescu, D., Murphy, E.G., and Shandling, B. 1990.Thymectomy in juvenile myasthenia gravis. J Child Neurol, 5:215-218

 

3.       Theodorescu, D., Cornil, I., Fernandez, B.J., and Kerbel, R.S. 1990.Overexpression of normal and mutated forms of HRAS induces orthotopic bladder invasion in a human transitional cell carcinoma. Proc Natl Acad Sci U S A, 87:9047-9051

 

4.       Cornil, I., Theodorescu, D., Man, S., Herlyn, M., Jambrosic, J., and Kerbel, R.S. 1991.Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression. Proc Natl Acad Sci U S A, 88:6028-6032

 

5.       Cornil, I., Theodorescu, D., Kerbel, R.S., and Poupon, M.F. 1991.Metastatic dissemination of cancer cells. Pathol Biol (Paris), 39:300-307

 

6.       Fu, X.Y., Theodorescu, D., Kerbel, R.S., and Hoffman, R.M. 1991.Extensive multi-organ metastasis following orthotopic onplantation of histologically-intact human bladder carcinoma tissue in nude mice. Int J Cancer, 49:938-939

 

7.       Kerbel, R.S., Cornil, I., and Theodorescu, D. 1991.Importance of orthotopic transplantation procedures in assessing the effects of transfected genes on human tumor growth and metastasis. Cancer Metastasis Rev, 10:201-215

 

8.       Theodorescu, D., Caltabiano, M., Greig, R., Rieman, D., and Kerbel, R.S. 1991.Reduction of TGF-beta activity abrogates growth promoting tumor cell-cell interactions in vivo. J Cell Physiol, 148:380-390

 

9.       Theodorescu, D., Cornil, I., Sheehan, C., Man, S., and Kerbel, R.S. 1991.Dominance of metastatically competent cells in primary murine breast neoplasms is necessary for distant metastatic spread. Int J Cancer, 47:118-123

 

10.   Theodorescu, D., Cornil, I., Sheehan, C., Man, M.S., and Kerbel, R.S. 1991.Ha-ras induction of the invasive phenotype results in up-regulation of epidermal growth factor receptors and altered responsiveness to epidermal growth factor in human papillary transitional cell carcinoma cells. Cancer Res, 51:4486-4491

 

11.   Theodorescu, D., Bergsma, D., Man, M.S., Elshourbagy, N., Sheehan, C., Rieman, D., and Kerbel, R.S. 1991.Cloning and overexpression of TGF-beta 1 cDNA in a mammary adenocarcinoma: in vitro and in vivo effects. Growth Factors, 5:305-316

 

12.   Theodorescu, D., Witchell, S., and Connolly, J. 1991.Chronic adult renal vein thrombosis: two unusual cases and a review of the literature. Int Urol Nephrol, 23:429-435

 

13.   Theodorescu, D., Binnington, A.G., and Connolly, J.G. 1992.The intestinoprostatic capsule anastomosis: functional and anatomic results in a canine model. Can J Surg, 35:169-172

 

14.   Wu*, S.P., Theodorescu, D*., Kerbel, R.S., Willson, J.K., Mulder, K.M., Humphrey, L.E., and Brattain, M.G. 1992.TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector. J Cell Biol, 116:187-196.*(equal first authors)

 

15.   Schuh, A.C., Theodorescu, D., Shalaby, F., and Breitman, M.L. 1993.Altered growth and spontaneous transformation of cells cultured from v-jun transgenic mice recapitulate wound-induced multistage tumorigenesis. Cell Growth Differ, 4:177-184

 

16.   Theodorescu, D., Connors, K.M., Groce, A., Hoffman, R.M., and Kerbel, R.S. 1993.Lack of influence of c-Ha-ras expression on the drug sensitivity of human bladder cancer histocultured in three-dimensions. Anticancer Res, 13:941-946

 

17.   Theodorescu, D., Sheehan, C., and Kerbel, R.S. 1993.TGF-beta gene expression depends on tissue architecture. In Vitro Cell Dev Biol, 29A:105-108

 

18.   Huang, F., Newman, E., Theodorescu, D., Kerbel, R.S., and Friedman, E. 1995. Transforming growth factor beta-1 (tgf-beta-1) is an autocrine positive regulator of colon carcinoma U9 cells in vivo as shown by transfection of a tgf-beta-1 antisense expression plasmid. Cell Growth Differ, 6:1635-1642

 

19.   Theodorescu, D. 1996. Genetic prognostic markers for transitional cell carcinoma of the bladder: From microscopes to molecules. J. Urol. 155(1):2

 

20.   Theodorescu, D., Russo, P., Zhang, Z.F., Morash, C., and Fair, W.R. 1996 Outcomes of initial surveillance of invasive squamous cell carcinoma of the penis and negative nodes. J Urol 155(5):1626-1631

 

21.   Theodorescu, D. 1996. Prostate Cancer - Our Patients’ Questions. J. Urol. 155(5):1661-1662

 

22.   Frierson, H. W., Theodorescu, D., and Hannnigan, M.C. 1997 Clinicopathological study of gamma-glutamyl transferase (GGT) in benign and malignant prostate. Mod Pathol 10(1):1-6.

 

23.   Lajvardi, A., Theodorescu, D., and Older R.O. 1997 A mullerian duct cyst presenting as a complex pelvic mass. J. Urol. 157(3):958.

 

24.   Herrel, D., Trachtenberg, J. and Theodorescu, D. 1997 Pelvic lymphadenectomy in prostate cancer: comparison of three surgical techniques. J. Urol. 157(4):1337-1339.

 

25.   Theodorescu, D., Broder, S. R., Boyd, J. C., Mills, S. E. and Frierson, H. W. 1997 The use of p53, bcl-2 and Rb protein expression as prognostic markers in localized carcinoma of the prostate. J. Urol. 158(1):131-137.

 

26.   Theodorescu, D. 1997 Prognostic factors for relapse in stage I testicular seminoma treated with surveillance - Comment. J. Urol 157(5):1709

 

27.   Harding M. and Theodorescu, D. 1997 Molecular biology: its role as a prognostic indicator for bladder cancer. Current Opinion in Urology 7: 282-286

 

28.   Lippert, M. C. and Theodorescu, D. 1997 The Hautmann neobladder with a chimney: a versatile modification. J Urol 158 (4): 1510-1512

 

29.   Theodorescu, D., Broder, S. R., Boyd, J. C., Mills, S. E., and Frierson, H. F., Jr. 1997 Chromogranin A as a long-term prognostic markers in localized carcinoma of the prostate. Cancer 80 (11): 2109-2119

 

30.   Theodorescu, D., Lippert, M. C., Broder, S. R., and Boyd, J. C. 1998 Early PSA failure following radical prostatectomy: The importance of surgical technique. Urology 51 (2): 277-282

 

31.   Theodorescu, D., Balcom, A., Churchill, B.M., and Khoury, A. E. 1998 Urethral replacement with vascularized tunica vaginalis: defining optimal form of use. J Urol 159 (5):1708-1711

 

32.   Theodorescu, D. 1998 Correlation between p53 over expression and response to bacillus calmette-guerin therapy in a high risk select population of patients with T1G3 bladder cancer - Comment. J Urol 159 (3):791

 

33.   Theodorescu, D., Laderoute K. R., Calaoagan J. M. and Gulding, K. M. 1998 Inhibition of human bladder cancer motility by genistein is dependent on epidermal growth factor receptor but not p21ras gene expression. Int J Cancer 78(6):775-782

 

34.   Crane C. H., Clark M., Petroni G., and Theodorescu, D. 1998 The Bladder Tumor Antigen (BTA) test: performance in patients undergoing pelvic irradiation for non bladder malignancies. Int J Radiat Oncol Biol Phys 43(1):73-77

 

35.   Theodorescu, D., Laderoute, K. R., and Gulding, K. M. 1998 Epidermal growth factor receptor regulated human bladder cancer motility is a phosphatidylinositol 3-kinase mediated process. Cell Growth Differ 9(11):919-928

 

36.   Theodorescu, D., Frierson, H. W. and Sikes R. A. 1999 Molecular analysis of surgical margins following radical prostatectomy for localized prostate cancer. J Urol 161(5):1442-1448

 

37.   Gray, M., Petroni G. and Theodorescu, D. 1999. Urinary function following radical prostatectomy: comparison of retropubic and perineal techniques. Urology 53(5):881-890

 

38.   Harding M. and Theodorescu, D. 1999 Prognostic markers for adenocarcinoma of the prostate: From microscopes to molecules. Cancer and Metastasis Reviews 17(4):429-37

 

39.   Broder, S. R., Frierson, H. W. and Theodorescu, D. 1999 Unusual case of non exophytic invasive penile squamous cancer arising from a chronic sinus tract. Scandinavian Journal of Urology & Nephrology  33(5):333-35

 

40.   Lippert, M. C., McClain, R., Boyd, J. C. and Theodorescu, D. 1999 Alternative Medicine Use in Patients Treated With Curative Intent for Localized Prostate Cancer. Cancer 86(12):2642-2648

 

41.   Gildea, J. J., Golden, W., Harding, M. A., and Theodorescu D. 2000 The phenotypic and cytogenetic analysis of T24T, a highly tumorigenic subline of the human bladder cancer cell line t24. Genes Chromosomes and Cancer 27(3):252-63

 

42.   Krupsky, T., Frierson, H. W., Petroni G., and Theodorescu, D. 2000 P53, Rb proteins and area weighted microvessel density are long term survival markers in localized carcinoma of the prostate. Urology 55(5):743-9

 

43.   Krupsky, T., Bissonette, E., Petroni, G., Theodorescu, D. 2000 Comparison of quality of life in patients treated by either radical prostatectomy or brachytherapy for clinically localized prostate cancer.  Urology 55(5):736-42

 

44.   Sheta, E. A., Harding, M. A., and Theodorescu, D. 2000 Vascular endothelial growth factor is transcriptionally regulated by cell density in prostate cancer cells. J Natl Cancer Inst 92(13):1065-73

 

45.   Im, D, Heise, C. E. A., Harding, M. A., O’Dowd, B. F., Theodorescu, D., and Lynch, K. R. 2000 Molecular cloning and characterization of a lysophosphatidic acid receptor, EDG-7, expressed in prostate. Mol Pharmacol 57(4):753-9

 

46.   Krupsky, T., Moskaluk, C.A., Boyd, J. C. and Theodorescu, D. 2000 Classical markers and area weighted microvessel density in the prediction of clinical stage of carcinoma of the bladder. Br J Urol 85(9):1027-32

 

47.   Gildea, J. J., Harding, M. A., and Theodorescu D. 2000 A novel and quantitative assay to measure genetic and pharmacologic effects on tumor cell motility and invasion.  BioTechniques 29:81-86

 

48.   Gardner, T. A., Bissonette, E., Petroni, G., Sokoloff, M., McClain, R., and Theodorescu, D., 2000 Operative and postoperative factors affecting length of stay following radical prostatectomy. Cancer 89: 424-430

 

49.   Theodorescu, D., Gillenwater, J.Y., and Koutrouvelis, P.G. 2000. Prostatourethral-rectal fistula formation following prostate brachytherapy: incidence and risk factors. Cancer 89: 2085-2091

 

50.   Sheta, E. A., Harding, M. A., and Theodorescu, D. 2001. Normoxic induction of active HIF-1a protein by cell density is dependent on Nitric Oxide and Ras / MAP Kinase mediated signaling pathways. Oncogene. 20(52):7624-34

 

51.   Coblentz, T., Mills, S. E. and Theodorescu, D., 2001. The value of second opinion pathology in the evaluation of patients referred for radical cystectomy. Cancer. 91(7):1284-90

 

52.   Fulmer, B., Petroni G, and Theodorescu, D. 2001. Prospective comparison of sexual and voiding function in patients treated by either radical prostatectomy or brachytherapy for clinically localized prostate cancer. Cancer. 91(11):2046-55

 

53.   Krupsky, T., Harding, M. A., and Theodorescu, D. 2001. The role of vascular endothelial growth factor in the tissue specific in vivo growth of prostate cancer cells. Growth Factors 18: 287-302

 

54.   Seraj, M. J., Gildea, J. J., Harding, M. A., and Theodorescu, D. 2001. Molecular determination of perivesical and lymph node metastasis following radical cystectomy for urothelial carcinoma of the bladder. Clinical Cancer research  7: 1516-1522

 

55.   Seraj, M. J., Gildea, J. J., Harding, M. A., and Theodorescu, D. 2001. Metastatic potential and metastasis related gene expression of lineage related human bladder cancer cell lines. Clinical and Experimental Metastasis  18: 519-525

 

56.   Fulmer, B., Petroni G, and Theodorescu, D. 2001. Psa velocity at tumor recurrence following radical prostatectomy: a surrogate marker for increased tumor aggressiveness in African American men. J Urol 166:1328-1331

 

57.   Smith, E. and Theodorescu, D. 2001. Evaluation of urinary continence and voiding function: Early results in men with the neourethral modification of the Hautmann orthotopic neobladder. J Urol 166: 1346-1349

 

58.   Santen, R. J., Fisch, M., Myers, C., Theodorescu, D.,  Petroni, G., and Cohen, R. 2001. Use of the Aromatase Inhibitor Anastrozole in the Treatment of Advanced Prostate Cancer. Cancer 92: 2095-2101

 

59.   Theodorescu, D., Sorensen, E. J. and Older R.O. 2001 Metastatic melanoma presenting as an ileal conduit filling defect J. Urol 166: 1393-1394

 

60.   Chen, C., Frierson, H. F., Haggerty, P. F., Theodorescu, D., Gregory, C. W., Dong, J.T. 2001. An 800 kb Region of Deletion at 13q14 in Human Prostate and Other Carcinomas. Genomics 77: 135-144

 

61.   Nicholson B, Schaefer G, Theodorescu D. 2001. Angiogenesis in prostate cancer: biology and therapeutic opportunities. Cancer Metastasis Rev. 20(3-4):297-319

 

62.   Gildea, J. J., and Theodorescu D. 2002. The Role of Ral A in Epidermal Growth Factor Receptor-regulated Cell Motility. Cancer Research 62: 982-985.

 

63.   Karns, L.R., Kisielewski, A., Gulding, K.M., and Theodorescu, D. 2002. Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts. BMC Biotechnol 1: 11

 

64.   Smith, E. Frierson, H. F., Mills, S. E., and Theodorescu, D. 2002. Gleason scores of prostate biopsy and radical prostatectomy specimens over a 10 period: Is there any evidence for systematic upgrading? Cancer. 94, 2282-7

 

65.   Chesson, J. and Theodorescu, D. 2002 Adrenal tumor with caval extension: case report and review of the literature. Scandinavian Journal of Urology & Nephrology 36, 71-3

 

66.   Coblentz, T., Bissonette, E., Petroni, G., and Theodorescu, D., 2002. Multimodality radiotherapy and androgen ablation in the treatment of clinically localized prostate cancer: Early results in high risk patients. Prostate Cancer and Prostate Diseases 5(3):219-25

 

67.   Coblentz, T. and Theodorescu, D., 2002. Modified inguinal lymphadenectomy in the management of high risk penile cancer. J. Urol 168(4 Pt 1):1386-9

 

68.   Maklouf, A., Bissonette, E., and Theodorescu, D., 2002. Comparison of the costs and charges associated with multimodality radiotherapy and radical prostatectomy in the treatment of clinically localized prostate cancer: Urol 60(4):656-60

 

69.   Theodorescu, D. 2003. Invited review: Molecular Pathogenesis of Proliferative and Progressive Urothelial Cancer. Histol Histopathol 18: 259-274

 

70.   Valicenti, R. K., Bissonette, E., Petroni, G., and Theodorescu, D. 2003. Comparison of Sexual Function and Satisfaction Between 3D Conformal Radiation Therapy and Transperineal Prostate Brachytherapy. J. Urol 168(6):2499-504

 

71.   Oxford, G. K., and Theodorescu, D. 2003. Invited Review: Small G proteins in cancer cell motility and invasion. Cancer Letters 189(2):117-28

 

72.   Harding, M, A., Gildea, J. J., and Theodorescu D. 2002 Functional Genomic Comparison of Lineage Related Human Bladder Cancer Cell Lines with Differing Tumorigenic and Metastatic Potentials by SKY, CGH and a novel method of Positional Expression Profiling. Cancer Research 62(23):6981-9

 

73.   Hall, J.D., Boyd, J.C., and  Theodorescu D. 2003. Why patients choose prostatectomy or brachytherapy for localized prostate cancer: results of a descriptive pilot survey. Urology 61: 402-407

 

74.   Miller, N. Bissonette, E., and Theodorescu, D. 2003. The impact of a novel neoadjuvant hormonal therapy on the quality of life of patients treated by brachytherapy for clinically localized prostate cancer? Cancer 97: 1203-1210

 

77.   Krupski, T., Bissonette, E., Theodorescu, D. 2003. Impact of prostate volume on voiding function and quality of life in patients treated by brachytherapy for clinically localized prostate cancer. European Urology 43: 467-472, 2003

 

78.   Bigler, D. and Theodorescu, D. 2003 A novel approach to understanding the effects of botanical extracts on human prostate cancer. Oncogene 22: 1261-1272

 

79.   Hall, J., Bissonette, E., Theodorescu, D. 2003. Motivations for use of complementary medicine in patients with localized prostate cancer treated with curative intent. British J. Urol  91: 603-607

 

80.   Nicholson, B. and Theodorescu, D. Molecular therapeutics in prostate cancer. Histol Histopathol, 18: 275-298, 2003.

 

75.   Gildea, J. J., Harding, M, A., and Theodorescu D. 2002. RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Research 62(22):6418-23

 

81.   Woolsey, J., Miller, N., and Theodorescu, D. 2003 Permanent interstitial brachytherapy for prostate cancer: a current review. World J Urol, 21: 209-219.

 

82.   Theodorescu, D. Molecular pathogenesis of urothelial bladder cancer. Histol Histopathol, 18: 259-274, 2003.

 

83.   Theodorescu, D. Phosphoinositide signaling in urological disease. J Urol, 169: 2394-2396, 2003.

 

84.   Oxford, G. and Theodorescu, D. 2003. The role of Ras superfamily proteins in bladder cancer progression. J Urol, 170: 1987-1993

 

85.   Horwitz, E.M., Miller, N., Uzzo, R.G., and Theodorescu, D. 2003. Brachytherapy for prostate cancer: follow-up and management of treatment failures. Urologic Clinics of North America 30: 737-750

 

86.   Nicholson, B. and Theodorescu, D. 2004 Angiogenesis and prostate cancer tumor growth. J Cell Biochem, 91: 125-150,

 

87.   Bassignani MJ, Moore Y, Watson  L. and Theodorescu, D. 2004. Pilot Experience with Real-Time Ultrasound Guided Percutaneous Renal Mass Cryoablation J. Urol  171(4):1620-3

 

88.   Maklouf, A., Krupski, T.A., Bissonette, E., and Theodorescu, D. 2004. The impact of increased number of sampled cores on the predictive accuracy of pathological grade and tumor distribution in the prostate biopsy. British J. Urol  93(3):271-4

 

89.   Ames C.D., Frierson, H.F., and Theodorescu D. 2004. Unusual case of recurrent low grade invasive and endophytic squamous cell carcinoma of the penis. Scand J Urol Nephrol, 38:3, 258-259.

 

90.   Miller, N., and Theodorescu, D. 2004. Quality of Life in Brachytherapy for Prostate Cancer: A Current Review. British J. Urol  94(4):487-91

 

91.   Gildea, J. J., Chen, C, Dong, J-T., and Theodorescu D. 2004. Suppression of motility of a human bladder cancer cell line by wild type PTEN/MMAC is dependent on its protein phosphatase activity. Oncogene 23(40):6788-97

 

92.   Theodorescu D, Gildea, J. J., Harding, M, A., Conaway, M., and Frierson, H.F. 2004. Reduced expression of metastasis suppressor rhogdi2 is associated with decreased survival for patients with bladder cancer. Clinical Cancer Research 10(11):3800-6

 

93.   Theodorescu D and Frierson, H.F. 2004. When is a negative node really negative: The relevance of molecular tools in the detection of lymph node metastasis. Urologic Oncology 22(3):256-9

 

94.   Bradley E, Bissonette, E., and Theodorescu, D. 2004. Determinants of long term quality of life and voiding function of patients treated with radical prostatectomy or permanent brachytherapy for prostate cancer British J. Urol  94: 1003-1009

 

95.   Nicholson, B., Harding, M, A., Conaway, M., Frierson, H.F. and Theodorescu D. 2004. Mapping the evolution of human metastatic bladder cancer. Cancer Research 64: 7813-7821

 

96.   Koutrouvelis, P.G., Theodorescu, D., Katz, S., Lailas, N., Hendricks, F. 2004. Brachytherapy of Prostate Cancer after Colectomy for Colorectal Cancer: Pilot experience J. Urol  173: 82-85; discussion 85-86

 

97.   Woolsey, J., Bissonette, E., Schneider, B., and Theodorescu, D. 2004 Prospective outcomes associated with migration from preoperative to intraoperative planned brachytherapy: a single center report. J Urol  172: 2528-2531

 

98.   Smith, S.,C., Oxford, G., and Theodorescu D. 2005. The promise of gene-expression analysis in bladder cancer: a clinician's guide. BJU Int. Apr;95(6):874-80

 

99.   Miller, N. Bissonette, E., and Theodorescu, D. 2005. Undetectable PSA at 6-12 months: a new marker for early success in hormonally treated patients following prostate brachytherapy Cancer Jun 15;103(12):2499-506

 

100. Copp, H., Bissonette, E., and Theodorescu, D., 2005. Multimodality radiotherapy and androgen ablation in the treatment of clinically localized prostate cancer in high risk patients. Urology 65(6):1146-51

 

101. Globus, T., Theodorescu, D., Frierson, H.F. Woolard, D. 2005. Terahertz spectroscopic characterization of cancer cells. SPIE Proceedings, Vol. 5692.

 

102.  Fletcher, S., and Theodorescu D. 2005. What is the best treatment for advanced prostate cancer: Surgery of radiation? Can J Urol (12 Suppl 1:58-61)

 

103.Theodorescu, D., Fliser, D., Wittke, S., Mischak, H. 2005. Pilot study of capillary electrophoresis coupled to mass spectrometry as tool to define potential prostate cancer biomarkers in urine. Electrophoresis. 26(14):2797-808

 

104.Titus, B., Harding, M., A., Guise, T., A., Conaway, M., Frierson, H.F. and Theodorescu D. 2005. The Role of Endothelin-1 in RhoGDI2 mediated suppression of human metastatic bladder cancer. Cancer Research 65(16):7320-7

 

105.Titus, B., Schwartz. and Theodorescu D. 2005. Rho proteins in cell migration and metastasis. Crit Rev Eukaryot Gene Expr. 15(2):103-14

 

106. Oxford, G., Owens, C., A., Foreman, T., A., and Theodorescu D. 2005. RalA and RalB: Antagonistic relatives in cancer cell migration. Cancer Research 65(16):7111-20

 

107. Keim, J., L., and Theodorescu D. 2006. Robot-assisted radical cystectomy in the management of bladder cancer. The ScientificWorld JOURNAL (in press)

 

108. Zürbig, P., Renfrow, M., B., Schiffer, E., Novak, J., Walden, M., Wittke, S., Just I., Pelzing M., Neususs C., Theodorescu, D., Root, K.E., Ross, M.M., and Mischak, H. 2006 CE-MS and CE-MS/MS are powerful platforms in clinical diagnosis and biomarker discovery Electrophoresis 27(11):2111-2125

 

109. Miller, N. and Theodorescu, D. 2006. Status of robotic cystectomy in 2005. World J Urol  24(2):180-7

 

110.Theodorescu, D., Wittke, S., Ross, M.,M., Mischak, H. and Frierson, H.F. 2006. Discovery and validation of novel urothelial cancer protein biomarkers Lancet Oncology 7(3):230-40

 

111. Smith, S.,C., Oxford, G., and Theodorescu, D. 2006. The metastasis associated gene CD24 is regulated by Ral GTPase and is a mediator of cell proliferation and survival in human cancer. Cancer Research 66(4):1917-22

 

112. Wu, Z., Siadaty, M. S., Riddick, G., Frierson, H. F., and Theodorescu, D. 2006. A novel method for gene expression mapping of metastatic competence in human bladder cancer. Neoplasia Mar;8(3):181-9

 

113. Copp, H., Chin, J. L., Conaway, M., and Theodorescu, D. 2006. Prospective evaluation of the prognostic relevance of molecular staging for urothelial carcinoma. Cancer Jul 1:107(1):60-6 

 

114. Wu, Z., Frierson, H. F., and Theodorescu, D. 2006. Conditional expression of PTEN alters the androgen responsiveness of prostate cancer cells. Prostate Jul1;66(10):1114-23

 

115. Fletcher, S., Frierson, H. F., and Theodorescu, D. 2006. Case matched comparison of contemporary radiation therapy to surgery in patients with locally advanced prostate cancer. Int. Journal of Radiation Oncology, Biology, Physics  (in press)

 

116. Rhee, J. and Theodorescu, D. 2006. Radical Cystectomy with Ileal Conduit Diversion: Early Prospective Evaluation of the Impact of Robotic Assistance. BJU Int. (in press).

 

 117. Moon, K., Stukenborg, G.,J., and Dan Theodorescu. 2006. Cancer incidence after localized therapy for prostate cancer. Cancer (in press) .

 

 118.Wu, Y., Conaway, M., and Dan Theodorescu. 2006. Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia. Oncogene (in press)

 

 119. Moon, K., and Dan Theodorescu. 2006. Does the saturation biopsy technique improve cancer detection. Nat Clin Pract Urol. (in press)

 

 120. Rinker-Schaeffer, C.W., O’Keefe, J.P., Welch, D.R. and Dan Theodorescu. 2006.  Metastasis Suppressor Proteins: Discovery, Molecular Mechanisms and Clinical Application. Clinical Cancer Research Jul 1:12(13):3882-9.

 

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BOOK CHAPTERS

1.       Kerbel, R.S., and Theodorescu, D. 1990. Tumor cell subpopulation interactions mediated by transforming growth factor beta may contribute to clonal dominance of metastatically competent cells in primary tumors, p.100‑113. In M.M. Burger, B. Sordat, and R.M. Zinkernagel (eds.), Cell Cell Interaction Karger, Basel.

 

2.       Theodorescu, D., and See W 1999. Chapter 2: Biology and molecular aspects of development and progression of bladder cancer. In M. J. Droller (ed.), Bladder cancer: current diagnosis and treatment. (in press)

 

3.       Theodorescu, D., and Krupsky, T 2000. Prostate cancer: Overview of biology, pathology, diagnosis and natural history. In M. J. Zevitz (ed.), E-Medicine Textbook of Urology (www.emedicine.com)

 

4.       Theodorescu, D., and Krupsky, T 2000. Prostate cancer: Management of localized disease. In M. J. Zevitz (ed.), E-Medicine Textbook of Urology (www.emedicine.com)

 

5.       Theodorescu, D., and Krupsky, T 2000. Prostate cancer: Brachytherapy. In M. J. Zevitz (ed.), E-Medicine Textbook of Urology (www.emedicine.com)

 

6.       Theodorescu, D., and Coblentz, T 2000. Bladder cancer. In M. Schwab (ed.), Cancer Encyclopedia. Springer, New York

 

7.       Theodorescu, D. 2000. Prostate cancer. In M. Schwab (ed.), Cancer Encyclopedia. Springer, New York

 

8.       Nicholson, B and Theodorescu, D. 2002. Chapter 25: Retroperitoneal Diseases. In Gillenwater, Grayhack, Howards, and Mitchell (eds.), Adult and Pediatric Urology, 4th edition.

 

9.       Nicholson, B and Theodorescu, D. 2002. Chapter 15: Molecular Therapeutics: Present and Future. In Godec, and Mydlo (eds.), Handbook of prostate cancer: biology, epidemiology, and therapeutic modalities 1st edition.

 

10.   Myers, C. E. and Theodorescu, D. 2002. Chapter 16: Orthomolecular and Herbal Therapies in Prostate Cancer. In Godec, and Mydlo (eds.), Handbook of prostate cancer: biology, epidemiology, and therapeutic modalities 1st edition.

 

11.   Theodorescu, D. 2003. Chapter 3: Molecular Pathogenesis of Proliferative and Progressive (Invasive) Urothelial Cancer. In M. J. Droller (ed.), American Cancer Society Atlas of Clinical Oncology: Bladder Cancer.

 

12.   Theodorescu, D. and Cohen, S.M. 2004. Chapter 2: Molecular Epidemiology. In M. J. Droller and A. P. Bassi (eds.), Bladder Cancer: From the Laboratory to Clinical Practice.

 

13.   Theodorescu, D. 2005. Biomarkers of Invasion and Metastases. In Lerner SP, Schoenberg M, Sternberg C (Eds): Textbook of Bladder Cancer. London: T&F-Informa.

 

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OTHER PUBLICATIONS (Extended Abstracts, Non Medline Indexed Publications)

1.       Theodorescu, D., and Kerbel, R.S. 1989. Overgrowth of metastatic cells in a primary tumor is mediated by nonmetastatic cells via transforming growth factor beta. p.403‑405. In M. Pannell (ed.), Surgical Forum. American College of Surgeons, Chicago.

 

2.       Theodorescu, D., Jones, P.A. and Kerbel, R.S. 1992. Elucidation of the roles of ha-ras and p53 in bladder cancer progression using a novel orthotopic assay system. Grand Rounds in Urology 1(3):1-6

 

3.       Gardner, T. A., Boyd, J. C. and Theodorescu, D., 1997 Factors predicting hospital length of stay in patients treated by radical prostatectomy. p.597-600. In S. Schwartz (ed.), Surgical Forum. American College of Surgeons, Chicago.

 

4.       Gray, M. and Theodorescu, D. 1997 Quality of life following radical prostatectomy: comparison of retropubic and perineal techniques. p.395-399. In S. Schwartz (ed.), Surgical Forum. American College of Surgeons, Chicago.

 

5.       Theodorescu, D. and Lippert, M. C. The ileal neobladder with a chimney and neourethral tube: A versatile modification. p.133-137. In S. Schwartz (ed.), Surgical Forum. American College of Surgeons, Chicago.

 

6.       Gardner, T. A., and Theodorescu, D. 1997. Diagnosis and Treatment of Prostate Cancer. Surgical Services Management 3 (12): 20-28

 

7.       Harding M. and Theodorescu, D. 2000 Molecular prognostic markers for adenocarcinoma of the prostate: News and Views. Urologic Oncology

 

8.       Theodorescu, D. 2000 Comparison of quality of life in patients treated by either radical prostatectomy or brachytherapy for clinically localized prostate cancer.  AUA News

 

9.       Theodorescu, D., Gillenwater, J.Y., and Koutrouvelis, P.G. 2001. Prostatourethral-rectal fistula formation following prostate brachytherapy: incidence and risk factors. Medical Updates, on Therapy, Diagnosis and Prevention

 

10.   Theodorescu, D., Prostate cancer staging: Should MR Imaging be used? 2001 Journal of Evidence-based Oncology

 

11.   Theodorescu, D. 2001 Alternative medicine use in patients treated by either radical prostatectomy or brachytherapy for clinically localized prostate cancer.  AUA News

 

12.   Theodorescu, D. 2002 The management of carcinoma in situ (CIS) of the bladder.  AUA News

 

13.   Theodorescu, D., Rabbani, F. Donat M. 2004. Followup in Urologic Oncology: A Practical Guide AUA Updates.

 

14.   Theodorescu, D., 2004. Cryotherapy for Cancer: Evolution and Science. Med Reviews

 

15.   Sims, T and Theodorescu, D., 2004. Treating Bladder Cancer in 2004.Coping Magazine.

 

 

 

 

 

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