P.O. Box 400319
fax:
(434) 924-3710
Office:
Room 129 Chemistry
Positions and Employment
Assistant
Professor, University
of Virginia,
Charlottesville,
VA
July 2005-July 2011
Associate Professor, University of Virginia, Charlottesville,
VA
Aug. 2011-present
Department of
Chemistry and Neuroscience Graduate Program
Research interests:
· Detection of
dopamine, adenosine, and serotonin
using electrochemical sensors
· Development of
new carbon nanotube-based biosensors
· Rapid-sampling
microdialysis with capillary
electrophoresis detection for monitoring
neurotransmitter changes
during
behavior
Postdoctoral
Researcher, University
of Michigan,
Ann
Arbor, MI
2003-2005
Advisors: Robert
Kennedy (Chemistry) and Terry Robinson (Psychology)
Research
topic: Capillary
electrophoresis analysis of microdialysis samples for
the detection
of rapid amino acid changes in the brain
Education
Ph.D.,
Chemistry (Analytical), University
of North Carolina,
Chapel Hill, NC
2003
Advisor: Mark Wightman
Dissertation: Electrochemical
detection of chemical dynamics in the rat brain
B.S.,
Chemistry, University
of Delaware,
Newark,
DE
1998
Honors
degree, summa
cum laude
Research
Advisor: Murray Johnston
Undergraduate thesis: Secondary
structure of oligonucleotides probed by MALDI
Current Grants and Funding
Camille Dreyfus Teacher-Scholar,
Dreyfus Foundation, 5/2010-4/2015, $75,000
“Tiny sensors for tiny organisms: measuring neurotransmitter dynamics
in the fruit fly brain”
National
Institutes
of Health,
National Institute of Mental Health, 7/15/09-5/31/14, $1,818,346
1R01MH085159: “Real-time measurements of neurotransmission in
Drosophila
melanogaster”
Eli Lilly Young Investigator Award,
Sept. 2007-Sept. 2010, $100,000
National Science Foundation,
Feb. 2007-Jan. 2012, $550,000
“CAREER: Carbon nanotube modified microelectrodes for insect
neurotransmitter detection”
Completed Funding
National
Institutes of Health, National Institute of Biomedical Imaging
and Bioengineering, Aug. 2007-July 2009, $275,000
R21: “An electrochemical adenosine sensor for in vivo applications”
Eli Lilly Young Investigator Award,
Sept. 2007-Sept. 2009, $100,000
American Heart Association,
July 2007- June 2009, $132,000
“Mechanisms of adenosine formation during ischemia”
Distinguished
Young
Investigator Award, Fund for
Excellence in Science and
Technology, University
of Virginia,
July 1,
2006-June 30, 2007, $50,000
“Monitoring
fast neurochemical changes using
capillary electrophoresis with electrochemical detection”
Jeffress
Memorial
Trust, Jan.
1-Dec.31, 2006, $25,000
“Development
of an electrochemical adenosine sensor”.
Awards and Fellowships
Society for
Electroanalytical Chemistry (SEAC) Young Investigator Award
2011
Camille Dreyfus Teacher-Scholar
2010
American Chemical Society PROGRESS/Dreyfus Foundation
Lectureship
2008
Eli Lilly Young Analytical Investigator Award
2007
Meade Endowment Honored Faculty
2007-2008
National Science Foundation CAREER award
2007-2012
NIH Postdoctoral Fellowship
2003-2005
• NIDA Institutional Training Grant
Charles N. Reilley Award
2002
• Presented by Pharmacia to the most outstanding
analytical graduate student
National Science Foundation Graduate Research
Fellowship
1998-2001
Professional
Service
Journal Advisory Board,
The Analyst
2008-2013
NSF Review Panel
2008
NIH
Chartered Member, EBIT Study Section
2011-2017
Refereed Publications
From work
done at
Virginia:
20.) M.J. Peairs,
A.E. Ross, and B.J.
Venton.
Comparison of Nafion- and overoxidizedpolypyrrole-carbon nanotube
electrodes for neurotransmitter detection. Anal.
Methods,
in press.
19.) C.B.
Jacobs, T.L. Vickrey, B.J.
Venton.
Functional groups modulate the sensitivity and electron transfer
kinetics of neurochemicals at carbon nanotube modified microelectrodes.
Analyst. 2011, 136, 3557 -
3565.
18.) H. Fang,
T.L. Vickrey, and B.J.
Venton.
Analysis of biogenic amines in a single Drosophila larva brain by
capillary electrophoresis with fast-scan cyclic voltammetry
detection. Analytical
Chemistry.
2011, 83, 2258–2264. PMC3058613.
17.) M.L.
Pajski, B.J.
Venton.
Adenosine release evoked by short electrical stimulations in striatal
brain slices is primarily activity dependent. ACS
Chemical Neuroscience. 2010, 1, 775-787.
PMC3016054
16.) S. Cechova,
A.M. Elsobky, B.J.
Venton.
Adenosine A1 receptors self-regulate adenosine release in the striatum:
evidence of autoreceptor characteristics. Neuroscience. 2010, 171,
1006-1015. PMC2991493
15.) Y. Xu and B.J.
Venton.
Rapid determination of adenosine deaminase kinetics using fast-scan
cyclic voltammetry. Physical
Chemistry Chemical Physics 2010, 12,
10027-10032.
14.)
C.B.
Jacobs, M.J. Peairs, and B.J. Venton. Carbon
nanotube based electrochemical sensors
for biomolecules. Analytica
Chimica Acta. 2010,
662,
105-127.
13.)
X. Borue, B. Condron, B.J. Venton. Both
synthesis and reuptake are critical for
replenishing the releasable serotonin pool in Drosophila.
Journal
of Neurochemistry. 2010, 113,
188-199.
12.)
Y. Xu and B.J.
Venton. Microelectrode
Sensing
of Adenosine/Adenosine-5’-triphosphate
with
Fast-Scan Cyclic Voltammetry. Electroanalysis.
in press.
11.)
T. L. Vickrey, B.
Condron, B.J. Venton. Detection
of endogenous dopamine changes in Drosophila using fast-scan cyclic
voltammetry. Analytical
Chemistry. 2009,
81, 9306–9313.
10.)
G. Shambat, A. Deberardinis, P. Reinke, B.J.
Venton, L. Pu, J. Bean, B. Chen, J. Tour.
Addition Reaction and Characterization of
Chlorotris(triphenylphosphine)iridium(I) on Silicon(111) Surfaces. Applied Surface Science. 2009, 255,
8533-8538.
9.)
S.E. Cooper and B.J. Venton. Fast-scan
cyclic voltammetry for the detection of tyramine and octopamine. Analytical
Bioanalytical Chemistry 2009, 394, 329-336.
8.)X.
Borue, S.E. Cooper, J. Hirsh, B. Condron, B.J.
Venton. Quantitative evaluation of
serotonin release and reuptake in Drosophila.
Journal Neuroscience Methods. 2009,
179, 300-308. NIHMSID # 112632
7.)
M.L. Huffman and B.J. Venton. Carbon
fiber microelectrodes for in vivo
applications. Analyst, 2009,
134, 18-24. NIHMS#110526 Pubmed
i.d.#
19082168
6.)
M.L. Huffman and B.J. Venton. Electrochemical
properties of different carbon-fiber
microelectrodes using fast-scan cyclic voltammetry.
Electroanalysis.
2008, 20, 2422-2428.
5.)
C. B. Jacobs, T.L. Vickrey, and B.J.
Venton. Measuring chemical events in
neurotransmission. Wiley Encyclopedia of
Chemical Biology, 2009, 3, 319-330.
4.)
A.M. Strand and B.J. Venton. Flame
etching enhances the sensitivity of
carbon-fiber microelectrodes. Analytical
Chemistry, 2008, 80,
3708–3715.
3.)
S. Cechova and B.J. Venton. Transient
adenosine efflux in the rat caudate-putamen.
Journal of Neurochemistry, 2008,
105, 1253-1263.
2.)
B.E. Kumara Swamy and B.J. Venton. Carbon
nanotube-modified microelectrodes for
simultaneous detection of dopamine and serotonin in vivo. Analyst, 2007, 132,
876-894.
*
This article was highlighted in Chemical Technology, 2007,
4,
T66.
1.)
B.E. Kumara Swamy and B.J. Venton. Subsecond
detection of physiological adenosine
concentrations using fast-scan cyclic voltammetry.
Analytical
Chemistry, 2007, 79, 744-750.
Work Previous to Virginia: (Note: published under
both Venton and Trafton.)
16.)
B.M. Kile, T.S. Guillot, B.J. Venton,
W.C. Wetsel, G.J. Augustine, R.M. Wightman.
Synapsins Differentially Control Dopamine and Serotonin Release.
Journal of Neuroscience, 2010, 30,
9762-9770. PMCID:
PMC2923550
15.) B.J. Venton
and R.M. Wightman. Pharmacologically
induced, subsecond dopamine transients in
the caudate-putamen of the anesthetized rat.
Synapse, 2007, 61, 37-39.
14.) B.J. Venton,
R.T. Kennedy, T.E. Robinson, S. Maren. Dynamic increases in
glutamate and GABA in the basolateral
amygdala during acquisition and expression of conditioned fear. European
Journal of Neuroscience, 2006,
12, 3391-3398.
13.) B.J.
Venton, P.E.M. Phillips, W.C.
Wetsel, D. Gitler, G. Augustine, P. Greengard, R.M. Wightman. Cocaine increases dopamine release by
mobilization of a synapsin-dependent reserve pool.
Journal
of Neuroscience, 2006, 26,
3206-3209.
12.) D. Gitler, J.
Feng, Y. Takagishi, V.M.
Pogorelov, R.M. Rodriguiz; B.J. Venton, P.E.M.
Phillips, Y. Ren, H.-T.
Kao, R.M. Wightman, P. Greengard, P, W.C. Wetsel, G.J. Augustine. Synaptic vesicle trafficking and drug
addiction in synapsin triple knockout mice.
Cell
Biology of Addiction, 2006,
341-359.
11.) C.J.
Watson, B.J. Venton, R.T.
Kennedy. In vivo
measurements of neurotransmitters by microdialysis
sampling. Analytical Chemistry,
2006,
78, 1391-1399.
10.) B.J. Venton,
T.E. Robinson, R.T. Kennedy. Transient changes in
nucleus accumbens amino acid
concentrations correlate with individual responsivity to the predator
fox odor
2,5-dihydro-2,4,5-trimethylthiazoline. Journal of Neurochemistry 2006,
96, 236-246.
9.) B.J.
Venton, H. Zhang, P.A. Garris, D.
Sulzer, P.E.M. Phillips, R.M. Wightman.
Real-time decoding of dopamine neurotransmission in the
caudate-putamen
during tonic and phasic firing. Journal
of Neurochemistry, 2003, 87, 1284-1295.
8.) B.J.
Venton and R.M. Wightman. Psychoanalytical
electrochemistry: dopamine
and behavior. Analytical
Chemistry, 2003,
75, 414A-421A.
7.) D.L.
Robinson, B.J. Venton, M.L. Heien,
R.M. Wightman. Detecting subsecond
dopamine release with fast-scan cyclic voltammetry in vivo. Clinical
Chemistry, 2003, 49, 1763-1773.
6.) P.A.
Garris, E.A. Budygin, P.E.M. Phillips, B.J.
Venton, D.L. Robinson, B.P. Bergstrom, G.V. Rebec, R.M. Wightman. A role for presynaptic mechanisms in the
actions of nomifensine and haloperidol. Neuroscience,
2003, 118,
819-829.
5.) B.J.
Venton, D.J. Michael, R.M.
Wightman. Correlation of local changes
in extracellular oxygen and pH that accompany dopaminergic terminal
activity in the rat caudate-putamen.
Journal
of Neurochemistry, 2003, 84,
373-381.
4.) K.P.
Troyer, M.L. Heien, B.J. Venton,
R.M. Wightman. Neurochemistry and
electroanalytical probes. Current
Opinion in Chemical Biology, 2002, 6, 696-703.
3.) B.J.
Venton, K.P. Troyer, R.M.
Wightman. Response times of carbon fiber
microelectrodes to dynamic changes in catecholamine concentration. Analytical Chemistry, 2002,
74, 539-546.
2.) D.L.
Robinson, P.E.M. Phillips, E.A. Boudygin, B.J.
Trafton, P.A. Garris, R.M. Wightman.
Sub-second changes in accumbal dopamine during sexual behavior
in male
rats. NeuroReport, 2001,
12, 2549-2552.
1.) B.D.
Bath, D.J. Michael, B.J. Trafton,
J.D. Joseph, P.L. Runnels, R.M. Wightman.
Subsecond adsorption of dopamine at carbon-fiber microelectrodes. Analytical Chemistry, 2000, 72,
5994-6002.
Book
Chapters
M.G. Roper,
C. Guillo, and B.J. Venton. High
speed electrophoretic separations. In
“Handbook of Capillary and Microchip Electrophoresis
and Associated Microtechniques” CRC Press: New York. J.P. Landers, editor, 2008.
last
updated 5/10/11
©
All
materials on this webpage are the
property of The Venton Research Group
