Jan. 15, 2019---Yan Lab reported by UVAToday, University of Virginia Health System Newsroom, UVA Connect, NBC29 and CBS19 for findings related to muscle and nerve protection by exercise. This article (Wilson et al) was selected as the best APS research articles of January 2019. A confocal microscopy image showing an overlap of the presynaptic neuron-specific class III β–tubulin (Tuj1) (Green) with the postsynaptic acetylcholine receptors (AchR) (Red) in plantaris muscle as an index of innervation at NMJ.

New Finding

Genetic screen reveals that Atg2-Atg18/Atg9, a protein complex with function to recruit autophagic membranes, plays a critical role in maintaining mitochondrial integrity and heart and muscle functions in Drosophila. (J Mol Cell Cardiol on Dec. 14, 2018)

New Member

Wenqing (Grace) Shen, a visiting Ph.D. student, has recently joined the lab from East China Normal University in Shanghai, China.

New Method

Fluorescence lifetime imaging (FLIM) shows heterogeneous decay rate of the fluorescence in a C2C12 myoblast transfected with pmitoABKAR. a FRET reporter gene for mitoAMPK.

"上醫治未病 Superior doctors prevent the disease, mediocre doctors treat the disease before evident, inferior doctors treat the full-blown disease."-----Huangdi Neijing (2600 BCE) First Chinese Medical Text