Jan. 15, 2019---Yan Lab reported by UVAToday, University of Virginia Health System Newsroom, UVA Connect, NBC29 and CBS19 for findings related to muscle and nerve protection by exercise. This article (Wilson et al) was selected as the best APS research articles of January 2019. A confocal microscopy image showing an overlap of the presynaptic neuron-specific class III β–tubulin (Tuj1) (Green) with the postsynaptic acetylcholine receptors (AchR) (Red) in plantaris muscle as an index of innervation at NMJ.
Genetic screen reveals that Atg2-Atg18/Atg9, a protein complex with function to recruit autophagic membranes, plays a critical role in maintaining mitochondrial integrity and heart and muscle functions in Drosophila. (J Mol Cell Cardiol on Dec. 14, 2018)
Wenqing (Grace) Shen, a visiting Ph.D. student, has recently joined the lab from East China Normal University in Shanghai, China.
Fluorescence lifetime imaging (FLIM) shows heterogeneous decay rate of the fluorescence in a C2C12 myoblast transfected with pmitoABKAR. a FRET reporter gene for mitoAMPK.