Aug. 28, 2019---Yan Lab Farewell Party (for Josh Drake) and Christmas Party at Yan Residence. We had a lot of fun!

New Finding

Genetic screen reveals that Atg2-Atg18/Atg9, a protein complex with function to recruit autophagic membranes, plays a critical role in maintaining mitochondrial integrity and heart and muscle functions in Drosophila. (J Mol Cell Cardiol on Dec. 14, 2018)

New Member

Dr. Robert (RJ) Shute has recently graduated with a Ph.D. degree from the University of Nebraska at Omaha studying the role of environmental temperature during exercise on markers related to mitochondrial biogenesis, mitophagy, myogenesis, and proteolysis.  Welcome to UVA, RJ!!

New Method

Fluorescence lifetime imaging (FLIM) shows heterogeneous decay rate of the fluorescence in a C2C12 myoblast transfected with pmitoABKAR. a FRET reporter gene for mitoAMPK.

"上醫治未病 Superior doctors prevent the disease, mediocre doctors treat the disease before evident, inferior doctors treat the full-blown disease."-----Huangdi Neijing (2600 BCE) First Chinese Medical Text