Yan Lab is featured by UVA Health Newsroom, UVA Today and NBC29 and New York Times for the work published at the Journal of Applied Physiology on "Exercise during pregnancy mitigates negative effects of parental obesity on metabolic function in adult mouse offspring"
We have discovered that endurance exercise training prevents onset of Freidrich's ataxia in mice along with improved mitochondrial function and reduced oxidative stress. The findings paved the way for clinical studies of the impact of endurance exercise in Freidrich's ataxia patients (Scientific Reports on Mar. 9, 2020)
Joshua Milstein is a second-year Ph.D. student at UVA majoring in Neuroscience, co-mentored by Drs. Ferris and Yan. Josh is interested in how exercsie can prevent and treat Alzheimer's disease.
We have invented a voluntary weightlifting model in mice, which promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway (FASEB Journal on Mar. 5, 2020)