New findings in our lab show that long-term aerobic exercise training can prevents the symptomatic onset of Friedreich's ataxia in a mouse model
We have discovered that endurance exercise training prevents onset of Freidrich's ataxia in mice along with improved mitochondrial function and reduced oxidative stress. The findings paved the way for clinical studies of the impact of endurance exercise in Freidrich's ataxia patients (Scientific Reports on Mar. 9, 2020)
Sable Thompson is a second-year medical student at UVA, who is interested in the the molecular mechanism of the benefits of exercise on mood disorders. Casey Bauchle is a first-year Ph.D. student at UVA, who is interested in the role of mitochondrial function/dynamics in the context of metabolic disease.
Welcome, Sable and Casey!!
We have invented a voluntary weightlifting model in mice, which promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway (FASEB Journal on Mar. 5, 2020)